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Overactive Bladder clinical trials

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NCT ID: NCT02485067 Completed - Overactive Bladder Clinical Trials

Clinical Study to Assess the Efficacy and Safety of THVD-201 in Patients With OAB

Start date: January 2015
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to assess the efficacy and safety of THVD-201(Combination of tolterodine and pilocarpine) in patients with Overactive bladder during the period of treatment, 12 weeks. This study also includes an open label extension period of an additional 12 weeks following the treatment to assess long-term efficacy and safety of THVD-201 in patients with Overactive bladder.

NCT ID: NCT02476175 Completed - Clinical trials for Urinary Incontinence

Add-on Mirabegron in Pediatric Patients With Refractory Overactive Bladder

Add-on-Mira
Start date: April 2013
Phase: Phase 3
Study type: Interventional

The objective is to evaluate the efficacy and safety of adding mirabegron to an antimuscarinic to treat urinary incontinence in children with Overactive Bladder that are refractory to antimuscarinics.

NCT ID: NCT02468830 Completed - Clinical trials for Urinary Incontinence

Pilot Study of Mirabegron in Pediatric Patients With Overactive Bladder

Mirabegron
Start date: April 2013
Phase: Phase 3
Study type: Interventional

The objective is to evaluate the efficacy and safety of mirabegron to treat urinary incontinence in children with Overactive Bladder that are refractory and/or intolerant to antimuscarinics.

NCT ID: NCT02468375 Completed - Overactive Bladder Clinical Trials

Prospective Study for Patient Perception of Treatment Satisfaction After Switching to Mirabegron in Patients With Overactive Bladder Who Were Unsatisfied With Efficacy of Antimuscarinic Therapy or Adverse Event.

Start date: June 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to measure the treatment satisfaction after switching to mirabegron in patient with Overactive Bladder(OAB) who were unsatisfied with efficacy of antimuscarinic therapy or adverse event. Patient will take the mirabegron 50mg/day for 12 weeks, and the satisfation of the therapy will be measured with Treatment Satisfaction Questionnaire(TSQ), Global Response Assessment(GRA), OAB-q short form, OAB Symptom Score and Willingness to continue Questions.

NCT ID: NCT02452879 Recruiting - Overactive Bladder Clinical Trials

Treatment, Parallel Assignment, Double Blind (Subject, Outcomes Assessor), Efficacy Study

Start date: October 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether electroacupuncture is effective in the treatment of overactive bladder.

NCT ID: NCT02447367 Completed - Overactive Bladder Clinical Trials

Investigate the Effect of Food on the Pharmacokinetic of JLP-1207 in Healthy Male Volunteers

Start date: July 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the pharmacokinetic drug interaction between Solifenacin and Tamsulosin in healthy male volunteers.

NCT ID: NCT02398578 Terminated - Overactive Bladder Clinical Trials

Cystoscopic Ablation Via RF Energy Clinical Trial

CARETI
Start date: February 2015
Phase: Phase 1/Phase 2
Study type: Interventional

Phase I/II study to assess the safety and performance of the Amphora OAB system for treatment of urgency and frequency with or without urge incontinence caused by an overactive bladder.

NCT ID: NCT02396160 Completed - Clinical trials for Urinary Incontinence

The Effect of Urox™ in the Treatment of Overactive Bladder and Urinary Incontinence

Start date: August 2013
Phase: N/A
Study type: Interventional

This study aims to assess the efficacy of a specialized herbal formula, Urox, versus control over 8 weeks, in a double blind, placebo controlled trial. 150 participants are being recruited, randomized and administered treatment or placebo for the period of 8 weeks after initial eligibility screening. Outcome measures include previously validated tools such as the 3 day symptom diary measuring self-recorded day frequency, nocturia, urgency and incontinence episodes. Quality of life improvements are being measured using the Incontinence Impact Questionnaire, Urinary Distress Inventory and the short version of the OverActive Bladder survey.

NCT ID: NCT02389270 Not yet recruiting - Overactive Bladder Clinical Trials

Urinary Neurotrophin Levels in Healthy Children

Start date: March 2016
Phase: N/A
Study type: Observational

The aim of this study is to analyse urinary neurotrophin levels in healthy children. Urine samples will be collected at 3 different times of day (morning, noon, and evening) at urge sensation from all age groups of children who gained bladder control, i.e. from 3-18 years of age. Urinary levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) normalised to urinary creatinine will be analysed. Age and daytime related variations will be reported for both boys and girls. These results will contribute to understanding the role of neurotrophins in the physiology of lower urinary tract and pathophysiology of idiopathic and secondary hyperactive bladder in children.

NCT ID: NCT02386072 Completed - Overactive Bladder Clinical Trials

A Prospective, Observational, Multicenter Study of Patients Following Initiation of a New Course of Treatment for Overactive Bladder (OAB)

PERSPECTIVE
Start date: January 5, 2015
Phase:
Study type: Observational

A study to identify factors that are associated with improved effectiveness in pharmacologic therapy of Overactive Bladder, from the patient perspective primarily measured by OAB-Q-SF (Overactive Bladder Questionnaire Short Form)