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Overactive Bladder clinical trials

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NCT ID: NCT05895045 Recruiting - Overactive Bladder Clinical Trials

Yoga for Treatment of Overactive Bladder in Pediatric Patients

Start date: July 2024
Phase: N/A
Study type: Interventional

The goal of this pilot study is to assess the impact of yoga as a treatment modality in pediatric patients age 8-18 diagnosed with idiopathic overactive bladder as measured by validated questionnaires and urinary biomarkers. The main question it aims to answer is: Does yoga help improve overactive bladder symptoms in this patient population? Participants will take part in a weekly yoga session for a total of 6 weeks with validated questionnaires and urinary samples for biomarkers to be completed at the beginning, middle and end of the study. This study will follow a cross-over study design and patients will receive standard of care while not in the active treatment arm.

NCT ID: NCT05878951 Recruiting - Clinical trials for Urinary Incontinence

Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms

Start date: July 13, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of our multi-center randomized single-blind study is to examine the safety and effect of intra-detrusor OnabotulinumtoxinA injections at the time of holium laser enucleation of the prostate (HoLEP) in men with overactive bladder symptoms with and without urge incontinence.

NCT ID: NCT05844059 Recruiting - Overactive Bladder Clinical Trials

Lower Urinary Tract Symptoms After Intravesical Therapy

LUTSI
Start date: April 21, 2023
Phase:
Study type: Observational

With this prospective, observational study, we would like to investigate the effect of instillation therapy using BCG or mitomycin C on short- and long-term irritative and obstructive lower urinary tract symptoms using validated questionnaires. The study will objectify the lower urinary tract symptoms and thereby provide better recommendations for therapy with mitomycin C or BCG.

NCT ID: NCT05799313 Recruiting - Overactive Bladder Clinical Trials

Home Versus Office Removal of Percutaneous Nerve Evaluation (PNE) Lead

STIM
Start date: June 7, 2023
Phase: N/A
Study type: Interventional

For women undergoing percutaneous nerve evaluation (PNE) for the treatment of overactive bladder the first step is the PNE interstim therapy trial. If the PNE works, patients may opt to have the interstim procedure. The purpose of this study is to see if patients who remove their PNE lead at home have the same satisfaction with the PNE trial as those women who have their lead removed in the office.

NCT ID: NCT05798403 Recruiting - Overactive Bladder Clinical Trials

Efficacy of Electroacupuncture Versus Solifenacin Succinate for Female Overactive Bladder

Start date: July 7, 2023
Phase: N/A
Study type: Interventional

Through a scientific and standardized multicenter, blinding, double-dummy, randomized controlled, noninferiority clinical trial study method, the investigators evaluated electroacupuncture as a safe and effective non-pharmacological treatment for OAB in women by comparison with Solifenacin Succinate.

NCT ID: NCT05772637 Recruiting - Overactive Bladder Clinical Trials

Clinical and Urodynamic Assessment of Bladder Sensation in Multiple Sclerosis

CUBS-MS
Start date: February 14, 2024
Phase: N/A
Study type: Interventional

The aim of the study is to assess the association between bladder sensations progression during bladder filling and severity of Overactive bladder (OAB) in patients with multiple sclerosis.

NCT ID: NCT05685433 Recruiting - Overactive Bladder Clinical Trials

A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

RECIPE
Start date: January 26, 2023
Phase: N/A
Study type: Interventional

A prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the eCoin® implanted tibial nerve stimulator in subjects with urgency urinary incontinence (UUI).

NCT ID: NCT05652036 Recruiting - Overactive Bladder Clinical Trials

Procedural Discomfort Related to Number of Intradetrusor Botox Injections

BIND
Start date: July 7, 2022
Phase: Phase 4
Study type: Interventional

Injection of intradetrusor OnabotulinumtoxinA (BTX-A) is a highly efficacious therapy with a reliable safety profile and demonstrable improvements in subjective and objective measures for overactive bladder (OAB) symptom control. This procedure can be performed in the office with an evidence-based standard dosing of 100 units for idiopathic OAB. This is a single-blinded, randomized control trial is to evaluate and optimize the technique for performing intradetrusor injections of BTX-A for idiopathic OAB. This trial proposes two different reconstitution and injection schema to study patient-centered outcomes related to procedural discomfort and symptom relief.

NCT ID: NCT05652023 Recruiting - Overactive Bladder Clinical Trials

Noninvasive Ultrasound Assessment of Detrusor Dysfunction

NUADD
Start date: April 20, 2023
Phase:
Study type: Observational

The purpose of this study is to test a new ultrasound method called Quantitative Ultrasound Bladder Vibrometry to detect abnormal bladder function.

NCT ID: NCT05557279 Recruiting - Overactive Bladder Clinical Trials

Urinary Microbiome Changes Following Administration of 500 mg of NDS-446 in Women With Dry OAB at 12 Weeks

Start date: January 1, 2023
Phase: Phase 4
Study type: Interventional

The purpose of this study is to learn about how the use of 500 mg of dried cranberry powder extract (NDS-446) changes the bacteria that normal reside in the bladder of women who don't have urinary leakage problems but do have problems with urinary urgency and frequency.