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Ovarian Torsion clinical trials

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NCT ID: NCT06324565 Recruiting - Adnexal Torsion Clinical Trials

Role of Preoperative D-dimer Levels in the Diagnosis of Adnexal Torsion

Start date: January 13, 2022
Phase:
Study type: Observational

Adnexal torsion is the fifth most common gynecologic emergency. Thirty percent of all cases of adnexal torsion occur in females younger than 20 years. Approximately 5 of 100,000 females aged 1-20 years are affected, with girls older than 10 years at increased risk because of hormonal influences and gonadal growth that result in an increased frequency of physiologic and pathologic masses. The most common clinical symptom of torsion is sudden-onset abdominal pain that is intermittent, non-radiating, and associated with nausea and vomiting in 62% and 67% of cases respectively. Moreover, abdominal tenderness is a clinical sign which is reported in up to 88% of patients with adnexal torsion. None of the following tests are useful in the diagnosis of adnexal torsion: leukocytosis, pyuria, C-reactive protein, and erythrocyte sedimentation rate. Actually, transabdominal ultrasonography is the imaging modality of choice with a sensitivity of 92% and specificity of 96% in detecting adnexal torsion. A second-line imaging tool in the diagnosis of adnexal torsion is magnetic resonance, which may require a sedation in selected cases. Consequently, there are no clinical or imaging criteria sufficient to confirm the preoperative diagnosis of adnexal torsion to date. Therefore, patients with a clinical suspicion for adnexal torsion should undergo emergent diagnostic laparoscopy.

NCT ID: NCT05098366 Recruiting - Ovarian Torsion Clinical Trials

Furosemide Use to Fill the Bladder of Pediatric Females Awaiting Pelvic Ultrasound

Start date: May 29, 2021
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to investigate whether or not furosemide causes the bladder to fill faster than IV fluids alone so that a pelvic ultrasound exam can be performed.

NCT ID: NCT05060120 Recruiting - Adnexal Torsion Clinical Trials

Biomarker Panel in Ovarian Torsion

Start date: September 12, 2021
Phase:
Study type: Observational

The overall goal of the project is to find a panel of novel biomarkers for early detection of ovarian torsion.

NCT ID: NCT03852615 Recruiting - Ovarian Torsion Clinical Trials

Ovarian Reserve After Ovarian Torsion

OTAMH
Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Ovarian torsion is a relatively common gynecological emergency, usually presenting as acute lower abdominal pain. Due to patient's presentation diversity, the diagnosis is clinical and requires integration of different factors and the exclusion of other non-gynecological pathologies. Surgery is the definitive treatment and may still be effective after several hours of symptoms. Delay in treatment can impact fertility adversely. The aim of this study is to evaluate the change in anti mullarian hormone before and after laparoscopic de-torsion of the ovary in our medical center compared to controls.