Ovarian Function Insufficiency Clinical Trial
Official title:
Ovarian Function After Hysterectomy With or Without Fimbriectomy or Salpingectomy
The impact of Hysterectomy with preservation of the ovaries on ovarian function has long been
controversial. studies have shown conflicting data regarding ovarian function after simple
Hysterectomy.
In recent years, there is a growing evidence that Salpingectomy or Fimbriectomy may have
preventive value reducing Ovarian and Primary Peritoneal carcinoma, but the safety and the
consequences regarding ovarian function have yet to be established.
The aim of this study is to evaluate ovarian function after Hysterectomy alone Vs.
Hysterectomy combined with salpingectomy or fimbriectomy
Status | Unknown status |
Enrollment | 60 |
Est. completion date | |
Est. primary completion date | June 2014 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Women undergoing Hysterectomy for Benign In dication (eg. Uterus Myomatous) before menopause Exclusion Criteria: - Menopause - known or suspected malignancy |
Country | Name | City | State |
---|---|---|---|
Israel | Kaplan Medical Center | Rehovot |
Lead Sponsor | Collaborator |
---|---|
Kaplan Medical Center |
Israel,
Bulent Tiras M, Noyan V, Ozdemir H, Guner H, Yildiz A, Yildirim M. The changes in ovarian hormone levels and ovarian artery blood flow rate after laparoscopic tubal sterilization. Eur J Obstet Gynecol Reprod Biol. 2001 Dec 1;99(2):219-21. — View Citation
Farquhar CM, Sadler L, Harvey SA, Stewart AW. The association of hysterectomy and menopause: a prospective cohort study. BJOG. 2005 Jul;112(7):956-62. — View Citation
Maseela T, Scheele R. [Hysterosalpingectomy. A contribution to the prevention of primary tubal neoplasms]. Fortschr Med. 1980 Jun 5;98(21):818-22. German. — View Citation
Morse AN, Hammer RA, Walter AJ, Baker S, Magtibay PM. Does hysterectomy without adnexectomy in patients with prior tubal interruption increase the risk of subsequent hydrosalpinx? Am J Obstet Gynecol. 2002 Dec;187(6):1483-5; discussion 1485-6. — View Citation
Riedel HH, Lehmann-Willenbrock E, Semm K. Ovarian failure phenomena after hysterectomy. J Reprod Med. 1986 Jul;31(7):597-600. — View Citation
Zalel Y, Lurie S, Beyth Y, Goldberger S, Tepper R. Is it necessary to perform a prophylactic oophorectomy during hysterectomy? Eur J Obstet Gynecol Reprod Biol. 1997 May;73(1):67-70. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Ovarian function | ovarian function measured by FSH , AMH and follicule count on ultra-sound | 60 days post-operative |
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