Ovarian Failure Clinical Trial
Official title:
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for the Treatment of Ovarian Failure
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Ovarian Failure
This patient funded trial aims to study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord derived mesenchymal stem cells (UC-MSCs) for the treatment of Ovarian Failure. Patients will receive a single intravenous infusion of UC-MSCs. The total dose will be 100 million cells. Patients will be evaluated within one month pre treatment and at 1, 6, 12, 24, 36, and 48 months post treatment for safety and efficacy. For patients with more severe disease an autologous Effector cells (activated lymphocytes) treatment will be utilized created from the patient's own cells obtained by apheresis. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01197456 -
Predictors of Ovarian Insufficiency in Young Breast Cancer Patients
|
||
Not yet recruiting |
NCT03674164 -
Fertility Preservation With Ovarian Tissue Freezing
|
N/A | |
Not yet recruiting |
NCT02280681 -
MAR With Artificial Gametes: Treatment Characteristics and Their Trade-offs Determining Treatment Preference
|
N/A | |
Completed |
NCT04776902 -
Effects of Ovarian Reserve on Sexual Satisfaction
|
N/A | |
Recruiting |
NCT04275700 -
Study of PRP in Women With Evidence of Diminished Ovarian Reserve
|
N/A | |
Completed |
NCT03398603 -
Is the Concentration of Anti-Muellerian Hormon (AMH) Depending on the Menstrual Cycle?
|
||
Not yet recruiting |
NCT04306185 -
Ovarian Fragmentation Study (Crespo Medical Team)
|
N/A | |
Not yet recruiting |
NCT03475758 -
Goserelin for Ovarian Protection in Premenopausal Patients Receiving Cyclophosphamide
|
Phase 2 | |
Not yet recruiting |
NCT06426771 -
Effect of Antimullerian Hormone Levels on the Inflammatory Index, Phytochemical Index and NRF Nutrient Density
|
||
Enrolling by invitation |
NCT04009473 -
Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation
|
Phase 1/Phase 2 | |
Completed |
NCT03040921 -
Uterine Transposition: Feasibility Study
|
N/A | |
Active, not recruiting |
NCT04444245 -
Ovarian Rejuvenation Using Platelet Rich Plasma (PRP) & Autologous Tissue Stromal Vascular Fraction (tSVF) and Cell Enriched tSVF
|
Phase 1 | |
Completed |
NCT06394466 -
Thyroid Function and Autoimmunity in Subfertility Women and Assisted Reproductive Therapy
|
||
Completed |
NCT03907618 -
Evaluation of HbA1c Levels and Ovarian Reserve and Type 1 Diabetes
|
||
Recruiting |
NCT05181748 -
Autologous Platelet Rich Plasma Intraovarian Infusion for Poor Responders
|
Phase 2/Phase 3 | |
Completed |
NCT04024449 -
Can Celiac Disease Affect Ovarian Function in Adolescent?
|
||
Completed |
NCT04163640 -
Ovarian Rejuvenation for Premature Ovarian Insufficiency and Poor Ovarian Response
|
N/A |