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Clinical Trial Summary

This first-in-human study will evaluate the Maximum Tolerated Dose (MTD) / the Recommended Phase 2 Dose (RP2D), safety, tolerability, anti-tumor activity, pharmacokinetics, pharmacodynamics and immunogenicity of AMT-151, a novel antibody-drug conjugate against folate receptor alpha, in patients with selected advanced solid tumors.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Adenocarcinoma
  • Adenocarcinoma of Lung
  • Adenocarcinoma, Mucinous
  • Advanced Cancer
  • Advanced Carcinoma
  • Advanced Solid Tumor
  • Carcinoma
  • Carcinoma, Endometrioid
  • Carcinoma, Ovarian Epithelial
  • Cystadenocarcinoma
  • Endometrial Adenocarcinoma
  • Endometrial Cancer
  • Endometrial Clear Cell Adenocarcinoma
  • Endometrial Endometrioid Adenocarcinoma
  • Endometrial Neoplasms
  • Endometrial Serous Adenocarcinoma
  • Lung Adenocarcinoma
  • Malignant Pleural Mesothelioma
  • Mesothelioma
  • Mesothelioma, Malignant
  • Ovarian Cancer
  • Ovarian Carcinoma
  • Ovarian Clear Cell Adenocarcinoma
  • Ovarian Clear Cell Carcinoma
  • Ovarian Endometrioid Adenocarcinoma
  • Ovarian Epithelial Cancer
  • Ovarian Mucinous Adenocarcinoma
  • Pancreatic Ductal Adenocarcinoma
  • Triple Negative Breast Cancer
  • Triple Negative Breast Neoplasms

NCT number NCT05498597
Study type Interventional
Source Multitude Therapeutics Inc.
Contact Jane Zhu
Phone 13917933915
Email juanjuan.zhu@multitudetherapeutics.com
Status Recruiting
Phase Phase 1
Start date January 25, 2023
Completion date October 30, 2024

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