Phase Ib Study of Chiauranib in Patients With Ovarian Cancer

Status Completed

Clinical Trial Summary

Chiauranib may stop the growth of tumor cells by blocking Aurora kinase B（Aurora B）、VEGFR/PDGFR/c-Kit、CSF-1R targets. This clinical trial is studying the efficacy and safety of chiauranib(50mg，QD，PO) works in treating patients with relapsed or refractory ovarian cancer, in the meantime, exploring the latent biomarkers accompany with chiauranib, as well as the relevancy of which and clinical benefit.

Clinical Trial Description

The purpose of this study is to assess the efficacy and safety include adverse events, vital signs, laboratory tests ,etc., of Chiauranib in ovarian cancer patients due to the outcomes of the phase I study, and to explore the relevance between the latent biomarkers of Chiauranib and clinical benefit. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03166891
Study type	Interventional
Source	Chipscreen Biosciences, Ltd.
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	December 15, 2017
Completion date	March 20, 2019

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