Ovarian Cancer Clinical Trial
Official title:
Evaluation of Docetaxel in Recurrent, Platinum Resistant, Refractory and Paclitaxel Refractory Ovarian Cancer and Primary Peritoneal Carcinoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing
so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of docetaxel in treating patients with
recurrent or refractory ovarian or primary peritoneal cancer.
OBJECTIVES: I. Estimate the antitumor activity of docetaxel in patients with paclitaxel- and
platinum-resistant, recurrent or refractory, ovarian epithelial or primary peritoneal cancer
who have failed on higher priority treatment protocols. II. Determine the nature and degree
of toxicity of docetaxel in this patient population.
OUTLINE: Patients receive docetaxel as a 1 hour continuous intravenous infusion. Courses are
repeated every 21 days. Treatment continues in the absence of unacceptable toxic effects or
disease progression. All patients are followed every 3 months for 2 years, every 6 months
for 3 years, and then until death.
PROJECTED ACCRUAL: A total of 23-56 patients will be accrued for this study.
;
Primary Purpose: Treatment
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