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NCT05218278 Clinical Trial

NFL Dynamics as a Predictor Factor in Patients With Out of Hospital Cardiac Arrest

Out-Of-Hospital Cardiac Arrest Clinical Trial

Official title:
Dynamics of Light Chain of NFL as a Predictor Factor of Neurological Outcome in Patients With Out of Hospital Cardiac Arrest

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05218278
Other study ID # IRP-2021/01-01
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date January 1, 2022
Est. completion date December 31, 2024

Study information
Verified date January 2022
Source University Medical Centre Maribor
Contact Matej Strnad, MD, PhD
Phone +38651225448
Email strnad.matej78@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To investigate the pharmacodynamics of light chain of NFL in patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable neurological outcome compared to those with non-favorable neurological outcome.

Description:

To investigate the serum levels of the light chain of NFL at different time points after ICU admission (12, 24, 30, 36, 42, 48 hours after ICU admission) patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable neurological outcome compared to those with non-favorable neurological outcome.

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date December 31, 2024
Est. primary completion date December 31, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - out-of-hospital cardiac arrest successfully resuscitated and admitted to the ICU Exclusion Criteria: - trauma, drowning, electrocution, less than 18 years of age,

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Slovenia University medical center Maribor Maribor

Sponsors (1)
Lead Sponsor Collaborator
University Medical Centre Maribor

Country where clinical trial is conducted

Slovenia, 

Outcome
Type Measure Description Time frame Safety issue
Primary The difference in the dynamics of serum NFL levels measurements in patients with favorable neurological outcome compared to patients with non-favorable neurological outcome NFL levels 3 years
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