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NCT04993716 Clinical Trial

Epidemiological Study on the Management of Out-of-hospital Cardiac Arrest Survivors in Champagne ArDEnnes

Out-of-hospital Cardiac Arrest Clinical Trial

— CASCADE  

Official title:
Epidemiological Study on the Management of Out-of-hospital Cardiac Arrest Survivors in Champagne ArDEnnes

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04993716
Other study ID # The CASCADE Study
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date October 4, 2021
Est. completion date December 31, 2023

Study information
Verified date July 2022
Source Centre Hospitalier de Troyes
Contact Stéphane Sanchez, MD
Phone +33625036892
Email stephane.sanchez@hcs-sante.fr
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

Out-of-hospital cardiac arrest (OHCA) is a public health problem, affecting 50,000 people per year in France. Intervention time (initiation of cardiopulmonary resuscitation (CPR) and advanced CPR) are associated with a better prognosis. Despite this, the latest published data show a very low overall survival (5%). Our territory has only three centers distributed hospitals with both a 24-hour coronary angiography platform and an intensive care unit. Finally, although 60% of ACEHs receive coronary angiography in the Île de France region, it is performed on only 15% of patients in the Reims University Hospital. Therefore, it seems essential to conduct a study on the reality of the support of ACEH and to study the clinical and biological factors as well as the influence of the geographical distribution of specialized technical platforms on the prognosis of patients.

Recruitment information / eligibility
Status Recruiting
Enrollment 294
Est. completion date December 31, 2023
Est. primary completion date December 31, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Patient victim of ACEH in the Champagne-Ardenne region admitted living in hospital. Exclusion Criteria: - patient under the age of 18

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• observational
Collect from a bank of biological samples, identification of prognostic factors associated with survival without serious neurological heavy sequelae

Locations
Country Name City State
France hospital center of Troyes Troyes Champagne Ardennes

Sponsors (1)
Lead Sponsor Collaborator
Stephane Sanchez

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Analysis of prognostic factors associated with survival without severe neurological sequelae (CPC 1-2) at 3 months among the following variables 3 months
Primary Analysis of prognostic factors associated with survival without severe neurological sequelae (CPC 1-2) with collection of a bank of biological samples, identification of clinical factors and targeted temperature control 12 months
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