Survival Study After Out-of-hospital Cardiac Arrest

Status Recruiting

Clinical Trial Summary

The purpose of this study is to determine if dual dispatch of ambulance, fire fighters and/or police in out-of-hospital cardiac arrest (OHCA), can reduce the time to cardiopulmonary resuscitation (CPR) and defibrillation, thus increasing survival.

Clinical Trial Description

Hypothesis If simultaneous dispatch of ambulance (EMS), firefighters and/or police is being initiated when an OHCA occurs, then the two latter units will be first at scene, before the ambulance crew, in ≥30% of the cases. We anticipate therefore that overall 30-days survival will increase on a national level from 9% to 12%.

Method During the period 110901 to 141231 all OHCA cases will be analyzed were the emergency medical communication centre (EMCC) has dispatched ambulance, firefighters and/or the police. Participating in the Saving More Lives in Sweden (SAMS) project are the following counties: Stockholm, Sodermanland, Jonkoping, Vastra Gotaland (VG Region), Halland, Dalarna, Jamtland, Kalmar and Uppsala. Data is collected by the units being dispatched and thereafter sent on line to a database managed by Registercentrum in Gothenburg (http://www.registercentrum.se/), administrators of the Swedish Cardiac Arrest Register.

Parameters obtained are:

- Time for dispatch of fire fighters and/or police (recorded digitally).

- Time for arrival to the patient.

- Verification if cardiac arrest or not.

- CPR performed by fire fighters or police before arrival of EMS.

- Automated External Defibrillator (AED) connected to the patient.

- If yes, was the first recorded rhythm shockable, i.e. ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT).

- Time to defibrillation.

Survival data during from the Swedish Cardiac Arrest Register (SCAR) will be obtained during the same time period from nine comparable Swedish regions not participating in the SAMS study. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02184468
Study type	Interventional
Source	Karolinska Institutet
Contact	Leif Svensson
Phone	+4686161000
Email	leif.svensson@ki.se
Status	Recruiting
Phase	N/A
Start date	September 2011
Completion date	December 2014

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05434910` - Blood Pressure and Cerebral Blood Flow After Cardiac Arrest	N/A
Active, not recruiting	`NCT03700125` - Pre-hospital ECMO in Advanced Resuscitation in Patients With Refractory Cardiac Arrest. ( SUB30 )	N/A
Completed	`NCT02527694` - CPR Quality Between Flexible Stretcher and Standard Stretcher in OHCA	N/A
Completed	`NCT02899507` - Prophylactic Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest	Phase 4
Completed	`NCT04085692` - Dispatcher-Assisted CPR: Low-Dose, High-Frequency Simulation-Based Training	N/A
Recruiting	`NCT05029167` - REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study)	N/A
Completed	`NCT04080986` - DOuble SEquential External Defibrillation for Refractory VF	N/A
Completed	`NCT04058925` - Tissue Oxygenation During Cardiopulmonary Resuscitation as a Predictor of Return of Spontaneous Circulation
Enrolling by invitation	`NCT05113706` - Does Bystanders Emotional State Influence Dispatcher-assisted Cardiopulmonary?Resuscitation
Completed	`NCT04219306` - Machine Learning Assisted Recognition of Out-of-Hospital Cardiac Arrest During Emergency Calls.	N/A
Completed	`NCT03881865` - P25/30 SSEPs and Neurological Prognosis After Cardiac Arrest
Recruiting	`NCT04993716` - Epidemiological Study on the Management of Out-of-hospital Cardiac Arrest Survivors in Champagne ArDEnnes
Completed	`NCT05062785` - Dose-Finding Study of Intranasal Insulin in Healthy Participants Insulin in Healthy Participants	Phase 1
Recruiting	`NCT06122337` - Systemic Evaluation of the Etiologies of Young Adults With Non-traumatic Out-of-hospital Cardiac Arrest
Not yet recruiting	`NCT04584463` - Factors Associated With CPC 1-2 in 110 Patients Admitted in French ICU for a Myocardial Infarction Complicated by an OHCA.
Recruiting	`NCT03355885` - Early-onset Pneumonia After Out-of-hospital Cardiac Arrest	N/A
Recruiting	`NCT05132387` - Wroclaw Out-Of-Hospital Cardiac Arrest Registry
Recruiting	`NCT02827422` - A Prospective, Multicenter Registry With Targeted Temperature Management After Out-of-hospital Cardiac Arrest in Korea	N/A
Completed	`NCT02646046` - Combining Performance of Call EMS and Simultaneous Chest Compressions in a Lone Rescuer CPR	N/A
Recruiting	`NCT02056509` - The Effect of Chest Compression and Ventilation Coordination During Cardiopulmonary Resuscitation.	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Survival Study After Out-of-hospital Cardiac Arrest — SAMS

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms