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Otitis clinical trials

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NCT ID: NCT00645112 Completed - Acute Otitis Media Clinical Trials

A Comparison of Safety and Efficacy of Cefdinir Oral Suspension Versus Azithromycin in Pediatric Subjects With Acute Otitis Media

Start date: November 2003
Phase: Phase 4
Study type: Interventional

To compare the safety and efficacy of cefdinir oral suspension, 7 mg/kg every 12 hours for 5 days, to azithromycin oral suspension 10 mg/kg/day (Day 1) then 5 mg/kg/day (Days 2-5) for a total of 5 days, in children between 6 months and 6 years of age, with AOM.

NCT ID: NCT00644943 Completed - Acute Otitis Media Clinical Trials

A Comparison of the Safety and Efficacy of Cefdinir Oral Suspension Versus Amoxicillin/Clavulanate in Pediatric Subjects With Acute Otitis Media

Start date: February 2003
Phase: Phase 4
Study type: Interventional

The primary objective is to compare the safety and efficacy of cefdinir oral suspension, 7 mg/kg/day ql2hrs for 5 days, to amoxicillin/clavulanate oral suspension 45 mg/kg/day (based on amoxicillin component), in divided doses, q12h for 10 days, in children between 6 months and 6 years of age, with AOM.

NCT ID: NCT00643292 Completed - Acute Otitis Media Clinical Trials

A Single, High-Dose Azithromycin Extended Release (60 mg/kg) Compared With 10 Days of High-Dose Amoxicillin Clavulanate in Children With Ear Infections at High Risk of Persistent/Recurrent Ear Infections

Start date: January 2003
Phase: Phase 3
Study type: Interventional

A phase 3 randomized, multicenter, double blind, double dummy study to assess the efficacy, safety, and compliance of a single dose of azithromycin extended release compared with a 10-day course of amoxicillin/clavulanate twice daily in children at high risk for persistent or recurrent ear infections

NCT ID: NCT00638534 Completed - Otitis Media Clinical Trials

Japanese Study Evaluating the Effects of Telithromycin in Children With Acute Otitis Media

Start date: February 2004
Phase: Phase 3
Study type: Interventional

The primary objective is to assess the safety of telithromycin (HMR3647) 20 mg/kg qd for 5 days in children with acute otitis media (AOM). Secondary objectives are to assess Efficacy, Pharmacokinetics and Acceptability of telithromycin 20 mg/kg qd for 5 days in children with AOM.

NCT ID: NCT00629694 Completed - Clinical trials for Otitis Media With Effusion

Adenoidectomy, Myringotomy and Tubes' Insertion vs Adenoidectomy and Myringotomy Alone in Children With Otitis Media With Effusion and Adenoid Hypertrophy

Start date: September 2007
Phase: Phase 2
Study type: Interventional

It is not unusual for several children operated for severe adenoid hyperthrophy causing breathing problems to have otitis media with effusion simultaneously. It is unknown whether adenoidectomy, myringotomy and tubes insertion is superior to adenoidectomy and myringotomy alone in terms of otitis media related quality of life and recurrence of otitis media several months after the operation. For this purpose a randomized trial is conducted including children operated for adenoid hyperthrophy and whose otitis media with effusion had caused minimal or no symptoms so far

NCT ID: NCT00622518 Completed - Acute Otitis Media Clinical Trials

Ear Drops for Children With Otitis Media

Start date: February 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if a commercially available homeopathic ear drop preparation is effective in reducing symptoms in children 6 months - 11 years old with acute otitis media. A total of 120 study patients with otitis media will be randomized to receive homeopathic ear drops, or no ear drops, in addition to receiving standard care. It is postulated that children using the ear drops will have more rapid resolution of symptoms and need fewer antibiotics than those randomized to not receive the ear drops.

NCT ID: NCT00617682 Completed - Otitis Media Clinical Trials

Maternal Immunization To Prevent Infant Otitis Media

Start date: October 2000
Phase: Phase 1/Phase 2
Study type: Interventional

The main objective of this study is to evaluate whether immunization with 9-valent pneumococcal conjugate vaccine (PNCRM9) during the third trimester of pregnancy interferes with active antibody production in offspring immunized with PNCRM7 (Prevnar) in the first six months of life.

NCT ID: NCT00581711 Completed - Otitis Media Clinical Trials

Improving Otitis Media Care With Clinical Decision Support

OMHIT
Start date: December 2007
Phase: Phase 3
Study type: Interventional

This protocol will prospectively develop a new electronic health record (EHR)-based health information technology (IT) intervention that a) summarizes Otitis Media (OM) care into clinically meaningful episodes-of-care, b) provides clinical decision support based upon evidence-based guidelines to primary care and ENT physicians working within an integrated physician network that uses a common EHR, and c) tests the additive effects on quality and resource utilization of providing feedback to physicians.

NCT ID: NCT00579189 Completed - Acute Otitis Media Clinical Trials

Phase III Study of an Otic Formulation in Acute Otitis Media With Tympanostomy Tubes

Start date: January 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if a topical otic formulation is safe and effective in treating middle ear infections in patients with ear tubes.

NCT ID: NCT00578474 Completed - Acute Otitis Media Clinical Trials

A Phase III Study of an Otic Formulation in Acute Otitis Media With Tympanostomy Tubes

Start date: December 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if an otic formulation is safe and effective in treating middle ear infections in patients with ear tubes.