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Otitis Media clinical trials

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NCT ID: NCT04423952 Withdrawn - Clinical trials for Chronic Otitis Media

Validity of the French Version of the Quality of Life Questionnaire COMQ12-FR

COMQ12-FR
Start date: July 2021
Phase:
Study type: Observational

The World Health Organization estimates that chronic otitis media could reach between 65 and 350 million people worldwide and thus be an important cause of medical consultation and prescription drugs. The medical care of chronic otitis is difficult, despite several medical and surgical treatment options. Moreover this pathology is gladly recurrent. The completion of a standardized questionnaire to track symptoms objectively over time is fundamental to verify the efficacy of specific treatments and to compare treatments. The quality of life measurement questionnaire related to chronic otitis media (COMQ-12) is a new questionnaire, validated in English, to assist the physician in evaluating chronic otitis media. The objective of this study is to translate and validate the test in French in children.

NCT ID: NCT03603626 Withdrawn - Clinical trials for Post-operative Analgesia

Preemptive Pregabalin in Myringoplasty

Start date: September 2015
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the effect of preemptive pregabalin on post-operative pain reduction after myringoplasty.

NCT ID: NCT03534219 Withdrawn - Acute Otitis Media Clinical Trials

Efficacy of the EarPopper Device in Children With Recurrent Otitis Media

Start date: July 24, 2018
Phase: N/A
Study type: Interventional

This is a randomized controlled clinical trial evaluating the efficacy of the EarPopper device (EP) in the reduction of episodes of acute otitis media (AOM) in children with recurrent otitis media. The control arm will be observational. The intervention arm will have the EP used.

NCT ID: NCT03347461 Withdrawn - Clinical trials for Otitis Media With Effusion in Children

Otiprio Versus Ciprodex Tympanostomy Tube Outcomes

Start date: October 2018
Phase: Phase 4
Study type: Interventional

Otolaryngologists routinely administer ear drops at the time of tympanostomy tube placement in order to prevent tube otorrhea; however, there is a lack of consensus as to which drops are the most effective, and whether a post-operative regimen should be used. Utilizing drops postoperatively places the onus of administration on parents who may have various difficulties in delivering the drops to their child's ears. Additionally, prescribing drops postoperatively is a health care cost. The purpose of this study is to determine if there is a difference in prevention of tympanostomy tube failure (defined as tube blockage or otorrhea) between Otiprio administered once intraoperatively, Ciprodex otic dropgs administered once intraoperatively, and Ciprodex otic drops administered intraoperatively with a postoperative course.

NCT ID: NCT02950311 Withdrawn - Clinical trials for Otitis Media With Effusion

Xylitol for Otitis Media

Start date: November 20, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled study of children, age 6 months to 3 years, with a diagnosis of Otis media with effusion (OME) based on examination by a provider at a Duke- affiliated otolaryngology clinic.

NCT ID: NCT02409693 Withdrawn - Clinical trials for Otitis Media With Effusion (OME)

Retrospective Analysis of Perioperative Anesthetic Care and Analgesia Management of Patient Undergoing Bilateral Myringotomy With Tube Insertion

Start date: April 2015
Phase: N/A
Study type: Observational

This is a retrospective chart review. The purpose of this study is to retrospectively examine the use of perioperative analgesics on the incidence of postoperative pain and emergence delirium in patients undergoing bilateral myringotomy with tube insertion (BTI), as well as events associated with treatment including postoperative vomiting and time to discharge.

NCT ID: NCT01908764 Withdrawn - Otitis Media Clinical Trials

Pharmacokinetic Study of AL-60371 Otic Suspension in Pediatric Subjects Following Tympanostomy Tube Surgery

Start date: November 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to describe the pharmacokinetics of AL-60371 otic suspension following two posologies of bilateral ototopical doses in pediatric subjects immediately after bilateral tympanostomy tube surgery.

NCT ID: NCT01775709 Withdrawn - Otitis Media Clinical Trials

Evaluation of a New Biocompatible Pressure Equalizing Tube

Start date: July 2012
Phase: N/A
Study type: Interventional

Otitis media is the most common illness in children and 5% to 10% of their symptom cause by fluids in their middle ear . The OME can cause hearing loss included poor development of speech and poor communication. The surgical procedure is considered simple and relatively safe, but several complications may occur after Pressure Equalizing tube insertion. The most prevalent complications are otorrhea, biofilm and formation of retraction pockets. Otorrhea occurs in 30% to 83% of children with tube and is mainly due bacterial contamination of the middle ear either from external ear canal or impaired Eustachian tube. Swimming can facilitate the entry of bacteria into the middle ear from the ear canal through the PE tubes, and this assumption is reinforced by the statistically significant association between the rate of otorrhea and the non-utilization of ear plugs in children who swim (from 47% in children who used ear plugs to 56% in those who did not).

NCT ID: NCT01485471 Withdrawn - Clinical trials for Middle Ear Infection

Spectroscopic Evaluation of Middle Ear Infection (Withdrawn)

Start date: June 2011
Phase:
Study type: Observational

Otitis media is more common in young children and it is estimated that 75% of all children experience at least one episode before the age of three. Otitis media is one of the common pediatric diagnoses and recurrent episodes account for the most commonly performed surgical procedure. Despite this a high degree of inaccuracy exists in diagnosis of this condition which depends on subjective assessment of the ear drum via direct visualization using an otoscope. Researcher can use Diffuse optical spectroscopy and diffuse optical imaging for the analysis of ear drum and the middle ear.

NCT ID: NCT01160055 Withdrawn - Clinical trials for Infections, Streptococcal

Study to Characterize and Identify Bacteria Causing Acute Otitis Media in Young Egyptian Children

Start date: October 2012
Phase: N/A
Study type: Observational

The purpose of this epidemiological study is to identify and characterize the bacteria causing Acute Otitis Media episodes in children aged >= 3 months to < 5 years in Egypt.