Otitis Media With Effusion Clinical Trial
Official title:
Evaluation of Microplastics Presence in Otitis Media With Effusion Material
Microplastic rate is increasing ib athmosphere. They can be found in lung, kidney, heart, even placenta. Otitis media with effusion (OME) is a clinical condition that is ver common in children. Biofilms are blamed in the pathogenesis of OME. Microplastics can include biofilms. Importance of microplastics for potential pathogens and their toxicity aspects should be enlighted with studies. This study aims to investigate presency of microplastics in middle ear fluid of patients with OME.
Status | Recruiting |
Enrollment | 40 |
Est. completion date | April 20, 2024 |
Est. primary completion date | April 20, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A to 18 Years |
Eligibility | Inclusion Criteria: - patients who were followed by bilateral OME at least for three months or one-sided OME at least for 9 months were enrolled to the study Exclusion Criteria: - Patients with craniofacial anomaly, cleft palate, had history of previous ear surgery were excluded |
Country | Name | City | State |
---|---|---|---|
Turkey | Erciyes University Medical School | Kayseri |
Lead Sponsor | Collaborator |
---|---|
Kerem Kökoglu |
Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Microplastic presence | They will be commented as yes / no. Microplastics Determination Method: It applied according to Prada et. al report. Fragments, except blood clots, were washed with a jet of filtered distilled water inside the laminar flow hood to remove any surface contamination and all samples were weighed inside closed glass flasks to the nearest 0.1 mg (Sartorius, Entris, Germany). A method for preparing biological samples for Nile Red staining, previously developed and tested, was followed. | from March 2024 to April 2024 |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03590912 -
Efficacy and Cost Analysis of Steroids in Treatment of Otitis Media With Effusion
|
Phase 4 | |
Completed |
NCT03611842 -
Study of the Expression of MMPs in OME in Children With Atrophy of the Eardrum
|
||
Not yet recruiting |
NCT01421199 -
Device Study to Evaluate the Detection and Characterization of Middle Ear Fluid in Children
|
N/A | |
Completed |
NCT01202578 -
Evaluation of the Tympanostomy Tube Delivery System
|
Phase 2/Phase 3 | |
Completed |
NCT00520039 -
Osteopathic Otitis Media Research Study
|
N/A | |
Completed |
NCT00629694 -
Adenoidectomy, Myringotomy and Tubes' Insertion vs Adenoidectomy and Myringotomy Alone in Children With Otitis Media With Effusion and Adenoid Hypertrophy
|
Phase 2 | |
Completed |
NCT00195611 -
Study of Streptococcus Pneumoniae in Nose and Throats of Infants With Acute Otitis Media
|
Phase 4 | |
Not yet recruiting |
NCT05402267 -
The Effects of Exosomes in Otitis Media With Effusion
|
||
Not yet recruiting |
NCT04584073 -
Secretory Otitis Media in Adenoids Hypertrophy Patients
|
N/A | |
Withdrawn |
NCT00736112 -
Food Allergy - Tubes - Adenoids (FATA) Trial
|
N/A | |
Completed |
NCT00546117 -
A Clinical Trial of Proton Pump Inhibitors to Treat Children With Chronic Otitis Media With Effusion
|
N/A | |
Withdrawn |
NCT02950311 -
Xylitol for Otitis Media
|
Phase 2/Phase 3 | |
Recruiting |
NCT05324696 -
Autoinflation: Alternative in the Treatment of Otitis Media With Effusion
|
N/A | |
Recruiting |
NCT05353569 -
Coherent Optical Detection of Middle Ear Disease
|
N/A | |
Completed |
NCT02282540 -
Novel Imaging of the Eustachian Tube; Patient Study
|
N/A | |
Not yet recruiting |
NCT03491098 -
The Efficacy of Nasal Steroids in Treatment of Otitis Media With Effusion: Acomparative Study
|
Early Phase 1 | |
Completed |
NCT01082029 -
Study of Anti-reflux Medication as a Potential Treatment for Glue Ear in Children
|
Phase 4 | |
Completed |
NCT00939796 -
Clinical Study of the Tympanostomy Tube Delivery System
|
N/A | |
Recruiting |
NCT02215681 -
Acupuncture Effect on Inflammatory Markers in Pediatric Otitis Media With Effusion: A Pilot Study
|
N/A | |
Completed |
NCT02183961 -
Three Methods Used in the Diagnosis of EER in Children With OME
|
N/A |