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Otitis Media, Suppurative clinical trials

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NCT ID: NCT06424704 Not yet recruiting - Clinical trials for Microbial Colonization

Chronic Suppurative Otitis Media Microbiology

Start date: May 15, 2024
Phase:
Study type: Observational [Patient Registry]

This study is planned to reveal the microbiological agents and drug sensitivities to these agents in patients diagnosed with chronic suppurative otitis media who complain of ear discharge.

NCT ID: NCT03456739 Not yet recruiting - Clinical trials for Suppurative Otitis Media

The Microbiome Variability and Antibiotic Resistance of Chronic Suppurative Otitis

Start date: April 20, 2018
Phase: N/A
Study type: Observational

ear swabs will be collected from 120 patients with established CSOM at the ear-nose-throat (ENT) outpatient clinic at the Ziv medical center, and 120 swabs will be taken from children with Otitis Media with Effusion (OME) undergoing elective tympanostomy tube insertion, serving as a control group. Ear swabs will be frozen at -80C until analysis.DNA will be purified from ear swabs, and amplified by PCR so that a barcoded 16S rRNA library from each subject will be generated. Using correlation analysis, we will compare between microbial compositions in chronic otorrhea patients vs. control groups.An additional ear swab will be collected from patients and cultured to test antibiotic resistance.