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Clinical Trial Summary

- To determine prevalence of local allergic rhinitis (LAR)

- To evaluate clinical characteristic and severity of local allergic rhinitis

- To measure changing of tryptase and Specific IgE for Dermatophagoides pteronyssinus (Dp) after nasal allergen provocation test (NAPT)


Clinical Trial Description

Children 8-18 years with NAR were recruited. A NAPT with Der p 1 solutions (NAPT-DP) at 200 AU/mL, 600 AU/mL and 2000 AU/mL at 15-minute interval was performed, respectively. The immediate responses to NAPT-DP were assessed using symptoms score, peak nasal inspiratory flow (PNIF) and acoustic rhinometry (ARM). The nasal tryptase and sIgE-DP were measured at baseline, 15 min and 1 h after positive NAPT-DP. Allergic rhinitis (AR) patients were used as positive control. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02271620
Study type Interventional
Source Mahidol University
Contact
Status Completed
Phase N/A
Start date January 2014
Completion date April 2016