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A Study of ZN-c3 in Combination With Gemcitabine in Subjects With Osteosarcoma

Osteosarcoma Clinical Trial

Official title:
A Phase 1/2 Dose Escalation and Dose Expansion Study of ZN-c3 in Combination With Gemcitabine in Adult and Pediatric Subjects With Relapsed or Refractory Osteosarcoma

Clinical Trial Summary

This is a phase 1/2 study of ZN-c3 in combination with gemcitabine in adult and pediatric subjects with relapsed or refractory osteosarcoma.

Clinical Trial Description

This is a phase 1/2 dose escalation and dose expansion study, evaluating the clinical activity and safety, pharmacodynamics, and pharmacokinetics of ZN-c3 in combination with gemcitabine in relapsed or refractory osteosarcoma. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04833582
Study type Interventional
Source K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Contact
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date August 1, 2021
Completion date December 30, 2023
View Details
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