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ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma — ISG/OS-2  

Osteosarcoma Clinical Trial

Official title:
ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma - Prospective Study (ISG/OS-2)

Clinical Trial Summary

This is a phase II multicentre, uncontrolled trial including patients ≤ 40 years with non-metastatic extremity high-grade osteosarcoma stratified according to P-glicoprotein expression

Clinical Trial Description

The main objective of the study is to evaluate the impact on event-free survival (EFS) of a multi-drug chemotherapy approach and mifamurtide treatment in patients with non-metastatic osteosarcoma of the extremities according to the expression of ABCB1/P-glycoprotein ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01459484
Study type Interventional
Source Italian Sarcoma Group
Contact
Status Completed
Phase Phase 2
Start date June 23, 2011
Completion date April 30, 2024
View Details
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