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High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma

Osteosarcoma Clinical Trial

Official title:
Randomized, Blinded, Placebo-Controlled Trial of High Dose Methotrexate With Leucovorin Rescue (HDMTX-LV) With or Without Glucarpidase in Osteosarcoma

Clinical Trial Summary

The purpose of this study is to demonstrate whether use of glucarpidase facilitates administration of the next cycle of chemotherapy as scheduled and improves safety and tolerability of HDMTX given with LV

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00634322
Study type Interventional
Source BTG International Inc.
Contact
Status Terminated
Phase Phase 2
Start date October 2008
Completion date April 2009
View Details
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