Study of Effectiveness of GEMDOX in Relapsed Osteosarcoma

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT03628209` - Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma	Phase 1/Phase 2
Completed	`NCT04651569` - An Analysis of the Efficacy of High Dose Isofosfamide Through Elastomer
Recruiting	`NCT04417062` - Olaparib With Ceralasertib in Recurrent Osteosarcoma	Phase 2
Active, not recruiting	`NCT04803877` - SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma	Phase 2

See also

Status

Clinical Trial

Phase

Active, not recruiting

NCT03628209 - Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma

Phase 1/Phase 2

Completed

NCT04651569 - An Analysis of the Efficacy of High Dose Isofosfamide Through Elastomer

Recruiting

NCT04417062 - Olaparib With Ceralasertib in Recurrent Osteosarcoma

Phase 2

Active, not recruiting

NCT04803877 - SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma

Phase 2

Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.

Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

NCT number	NCT04651179
Study type	Observational
Source	Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna
Contact
Status	Completed
Phase
Start date	April 24, 2020
Completion date	November 23, 2021

Study of Effectiveness of GEMDOX in Relapsed Osteosarcoma

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms