Efficacy of Plyometrics to Increase Bone Mass in Men With Osteopenia

Osteopenia Clinical Trial

Official title:

Efficacy of Plyometrics to Increase Bone Mass in Men With Osteopenia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00572104
• Other study ID #: 1095877
• Secondary ID: R03AR055738
• Status: Completed
• Phase: N/A
• First received: December 10, 2007
• Last updated: October 6, 2016
• Start date: January 2008
• Est. completion date: November 2013

Study information

• Verified date: October 2016
• Source: University of Missouri-Columbia
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

This study will compare the ability of two types of long term (12 months) weight-bearing exercise treatments (1. high-intensity jumping and 2. weight lifting) to increase bone mass of the total body, spine and hip in physically active men with osteopenia.

Description:

The overall goal of this project is to determine the efficacy of chronic (12 months) plyometric jump training exercise on bone mineral density (BMD) and markers of bone turnover in physically active males cyclists diagnosed with osteopenia below normal bone mineral density of the lumbar spine or hip.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 38
• Est. completion date: November 2013
• Est. primary completion date: November 2013
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 25 Years to 60 Years

Eligibility

Inclusion Criteria:

• Male

• Age 25-60 years

• No symptoms of disease

• Currently participating in cycling activities an average of 4 hr/wk for the previous 24 months

• Osteopenia of the lumbar spine and/or hip (T score < -1.0 and > -2.5 )

Exclusion Criteria:

• Medications or supplements that affect bone metabolism or prevent exercise

• Previous or current medical condition affecting bone health

• Osteoporosis of the lumbar spine and/or hip (T score > -1.0 or < -2.5)

• Cardiovascular disease

• Metallic implants

• Current smoker

• Current regular participation in high-intensity resistance training and/or plyometrics

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Bone Diseases, Metabolic
• Osteopenia

Intervention

Other:
• resistance exercise
12 month training intervention of weight resistance exercise. All participants receive a daily calcium and vitamin D supplement
• plyometric exercise
12 month training intervention of plyometric exercise. All participants receive a daily calcium and vitamin D supplement

Locations

Country	Name	City	State
United States	University of Missouri-Columbia; McKee Gym	Columbia	Missouri

Sponsors (3)

Lead Sponsor	Collaborator
University of Missouri-Columbia	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Bone Mineral Density		12 months	No
Secondary	Serum markers of bone turnover		3 months	No
Secondary	Serum hormones regulating bone turnover		3 months	No