CONDOR Study of Osteonecrosis of the Jaws (TMJ)

Status Completed

Clinical Trial Summary

The purpose of this study was to examine risk factors for osteonecrosis of the jaw (ONJ), including the possible association with bisphosphonates (BPs). This study used the research infrastructure from the three NIDCR-funded dental practice-based research networks (DPBRN, PEARL, PRECEDENT). De-identified data from the DPBRN were merged with comparable de-identified data from PEARL and PRECEDENT to form a single trans-PBRN data set used for analysis.

Clinical Trial Description

The aims of this study were to (1) test the hypothesis that (BP) treatment is a risk factor for (ONJ); (2) to test the hypothesis that dental diseases (particularly periodontal disease), and invasive dental procedures such as dental extractions are true risk factors for (ONJ). ;

Study Design

Observational Model: Case Control, Time Perspective: Retrospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01130389
Study type	Observational
Source	Dental Practice-Based Research Network
Contact
Status	Completed
Phase	N/A
Start date	January 2007
Completion date	September 2008

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See also
Status	Clinical Trial	Phase
Completed	`NCT01666106` - Osteonecrosis of the Jaw (ONJ) Case Registry
Not yet recruiting	`NCT06419010` - Leukocyte- and Platelet-Rich Fibrin in the Surgical Treatment of Medication-related Osteonecrosis of the Jaw	N/A
Enrolling by invitation	`NCT05329558` - Local and Systemic Changes in Osteonecrosis of the Jawbone
Completed	`NCT01201330` - DPBRN Retrospective Cohort Study of Osteonecrosis of the Jaw	N/A
Completed	`NCT01967160` - Osteonecrosis of the Jaw (ONJ) and Infection Among Nordic Cancer Patients Treated With XGEVA™ or Zoledronic Acid
Recruiting	`NCT06457776` - Medication Related Osteonecrosis of the Jaws (MRONJ) in a Cohort of Patients Treated by Antiresorptive Drugs