Clinical Outcome of Surgical Treatment for Osteochondral Lesions of the Talus

Osteochondral Lesion of Talus Clinical Trial

Official title:

Clinical Outcome of Surgical Treatment for Osteochondral Lesions of the Talus

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05476692
• Other study ID #: OCD of the talus
• Status: Not yet recruiting
• Start date: October 1, 2022
• Est. completion date: November 1, 2023

Study information

• Verified date: July 2022
• Source: Assiut University
• Contact: Mena Magdy
• Phone: 01272640608
• Email: menamagdy2353794[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Assess clinical and radiological outcome of the various surgical techniques for treatment of osteochondral lesions of the talus

Description:

Osteochondritis dissecans (OCD) of the talus is a subchondral bone pathology that presents as an osteochondral lesion of the talar dome with consequent articular cartilage abnormalities. Osteochondral lesions of the talus (OLT) are frequent after acute ankle trauma. The natural history of the OLT remains unclear due to paucity of longitudinal follow-up studies. Various treatment strategies have been described for OLT, including conservative treatment and operative treatment However, the current literature does not allow firm evidence-based recommendations concerning the treatment to be established ; Microfracture is the most common reparative surgery for osteochondral lesions of the talus (OLTs). While shown to be effective in short- to midterm outcomes, the fibrocartilage that microfracture produces is both biomechanically and biologically inferior to that of native hyaline cartilage and is susceptible to possible deterioration over time following repair . Arthroscopic debridement (AD) for the osteochondral lesions of the talar dome (OLT) was widely documented in the nineties with satisfactory results. However, in modern treatment algorithms, its role is not described. A frequently used instrument for assessing outcome after ankle and hindfoot injuries is the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score .

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 40
• Est. completion date: November 1, 2023
• Est. primary completion date: October 1, 2023
• Gender: All
• Age group: 15 Years to 60 Years

Eligibility

Inclusion Criteria:

• Age from 15 to 60 years old.

• Traumatic and degenerative etiology.

• without ankle deformity.

• No inflammatory arthritis.

• Absent or corrected ligamentous instability

Exclusion Criteria:

• Older than 60 years old and younger than 15 years old.

• Charcot ankle.

• Vascular injury.

Related Conditions & MeSH terms

• Osteochondral Lesion of Talus

Intervention

Other:
• AOFAS score and VAS
Clinical outcome by the Visual analogue scale (VAS) and the American Orthopaedic Foot and Ankle (AOFAS) score.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	clinical outcome of the various surgical techniques for treatment of osteochondral lesions of the talus	clinical outcome of the various surgical techniques for treatment of osteochondral lesions of the talus , Clinical outcome by the AOFAS score ( American Orthopaedic Foot and Ankle Society), the higher score means the better outcome and the lower score means the worse outcome	1 year

External Links

•   Long-term Outcomes of Microfracture for Treatment of Osteochondral Lesions of the Talus
•   Management of Osteochondral Lesions of the Talar Dome
•   Osteochondritis dissecans of the talus