Osteochondral Lesion of Talus Clinical Trial
Official title:
Clinical Outcome of Surgical Treatment for Osteochondral Lesions of the Talus
Assess clinical and radiological outcome of the various surgical techniques for treatment of osteochondral lesions of the talus
Osteochondritis dissecans (OCD) of the talus is a subchondral bone pathology that presents as an osteochondral lesion of the talar dome with consequent articular cartilage abnormalities. Osteochondral lesions of the talus (OLT) are frequent after acute ankle trauma. The natural history of the OLT remains unclear due to paucity of longitudinal follow-up studies. Various treatment strategies have been described for OLT, including conservative treatment and operative treatment However, the current literature does not allow firm evidence-based recommendations concerning the treatment to be established ; Microfracture is the most common reparative surgery for osteochondral lesions of the talus (OLTs). While shown to be effective in short- to midterm outcomes, the fibrocartilage that microfracture produces is both biomechanically and biologically inferior to that of native hyaline cartilage and is susceptible to possible deterioration over time following repair . Arthroscopic debridement (AD) for the osteochondral lesions of the talar dome (OLT) was widely documented in the nineties with satisfactory results. However, in modern treatment algorithms, its role is not described. A frequently used instrument for assessing outcome after ankle and hindfoot injuries is the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score . ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT04475341 -
Osteochondral Lesions Under 15mm2 of the Talus; is Iliac Crest Bone Marrow Aspirate Concentrate the Key to Success?
|
N/A | |
| Enrolling by invitation |
NCT03856021 -
Microfracture vs. Microfracture and BMAC for Osteochondral Lesions of the Talus
|
N/A | |
| Active, not recruiting |
NCT02345564 -
Clinical and Radiological Results of Osteochondral Repair Using MaioRegen in Knee and Ankle Surgery
|
N/A | |
| Active, not recruiting |
NCT01347892 -
DeNovo NT Ankle LDC Study
|
N/A | |
| Active, not recruiting |
NCT03750253 -
Extracorporeal Shock Wave Therapy for Pain-Relief After Arthroscopy for Osteochondral Lesions of the Talus
|
N/A | |
| Recruiting |
NCT06358807 -
Microfracture With Platelet Rich Plasma Gel Injection for Osteochondral Lesion of the Talus
|
N/A | |
| Completed |
NCT04194970 -
Monitoring of Weight Bearing Protocols Via Mobile Application and Pressure Sensors.
|
N/A | |
| Enrolling by invitation |
NCT02338375 -
Safety and Efficacy of Allogenic Umbilical Cord Blood-derived Mesenchymal Stem Cell Product
|
Phase 0 | |
| Withdrawn |
NCT05741983 -
AMIC vs. MFx in the Ankle
|
N/A | |
| Enrolling by invitation |
NCT04132076 -
Treatment Outcome After Ankle Joint Surgeries
|