Patient Specific Instrumentation in TKR

Status Completed

Clinical Trial Summary

Clinical Trial Description

This is a randomised control trial to assess the benefits of using patient specific instrumentation in total knee replacement surgery. Patient specific instrumentation is an individualised system for total knee replacement surgery. The system has been marketed and is already in use in some centres. The process is similar to traditional knee replacement surgery but approximately 6 weeks prior to the operation patients will undergo an MRI scan of their knee, hip and ankle. From this data the dimensions and rotation of the knee can be accurately measured, and a custom made jig can be made specific to that patients anatomy. The jig is used intra-operatively to make accurate bone cuts according to this pre-operative plan, the type of implant used remains the same but the sizing of the components, and alignment of the implant is expected to improve. This study assesses any improvement in implant alignment in using the patient specific instrumentation, any improved intra-operative outcomes and any long term clinical outcome improvements for patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02096393
Study type	Interventional
Source	Sheffield Teaching Hospitals NHS Foundation Trust
Contact
Status	Completed
Phase	N/A
Start date	September 2013
Completion date	June 18, 2020

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03277066` - A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis	Phase 2
Recruiting	`NCT03090698` - Outcomes of Injections in Patients Waiting for Total Knee Replacement	Phase 4
Completed	`NCT02556710` - A Study to Evaluate the Efficacy & Safety of an Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee	Phase 3
Completed	`NCT02242435` - A Multiple Injection Study Evaluating Safety and Efficacy of Ampion in Osteoarthritis	Phase 3
Withdrawn	`NCT02237846` - Clinical Study of Umbilical Cord Tissue Mesenchymal Stem Cells (UC-MSC) for Treatment of Osteoarthritis	Phase 1/Phase 2
Completed	`NCT01849445` - Targeted Rehabilitation to Improve Outcome After Knee Replacement- A Physiotherapy Study	N/A
Completed	`NCT01704157` - A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cryo-Touch III Device	N/A
Active, not recruiting	`NCT01374230` - Long-Term Multicenter Evaluation of the E1® Tibial Bearing	N/A
Completed	`NCT02156440` - Cross-over Study of the Efficacy and Safety of SierraSil Joint Formula 14 in Osteoarthritis of the Knee	Phase 2
Completed	`NCT01410409` - Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement	N/A
Not yet recruiting	`NCT01270412` - Platelet Rich Plasma (PRP) as a Treatment for Knee Osteoarthritis PRP as a Treatment for Knee Osteoarthritis	Phase 2/Phase 3
Completed	`NCT01207115` - A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee	Phase 2
Completed	`NCT00970008` - Exploring Massage Benefits for Arthritis of the Knee	Phase 2
Completed	`NCT00988091` - Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee	Phase 3
Completed	`NCT01331278` - A Comparative Study of Knee Systems	Phase 4
Completed	`NCT00531427` - Buprenorphine Transdermal System (BTDS) in Subjects w/Mod-sev Osteoarthritis (OA) Chronic Pain of Knee	Phase 3
Completed	`NCT00792727` - HKT-500 in Adult Patients With Osteoarthritis (OA) Knee Pain	Phase 3
Completed	`NCT00449696` - Gel-200 Versus Placebo in Osteoarthritis of the Knee	Phase 3
Completed	`NCT04145011` - Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain	N/A
Completed	`NCT01430559` - Effect Of Meloxicam Versus Placebo In Mainland Chinese Patients With Osteoarthritis Of The Knee	N/A