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Ossification, Heterotopic clinical trials

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NCT ID: NCT05648916 Enrolling by invitation - Clinical trials for Heterotopic Ossification

Celebrex and HO Study

Start date: August 2, 2022
Phase:
Study type: Observational

The primary goal of this observational study is to demonstrate the incidence of heterotopic ossification (HO) in patients with cementless total hip joint replacement surgery over time and secondly, demonstrate the relationship between celecoxib and HO formation. Lastly, investigators will examine the relationship between HO and patient-reported outcome measures (PROMs).

NCT ID: NCT04867278 Enrolling by invitation - Acetabular Fracture Clinical Trials

Heterotopic Ossification Prophylaxis

Start date: May 9, 2021
Phase: N/A
Study type: Interventional

One complication that can occur after surgery on the acetabulum is the development of bone in abnormal places such as muscle and soft tissues. There is some evidence that a single dose of radiation to the surgical site within 3 days of surgery will prevent this abnormal bone from forming. However, there are no high quality studies proving that radiation works any better than doing nothing at all. The purpose of our study is to determine whether there is a difference in abnormal bone formation after acetabular surgery when patients are treated with external beam irradiation versus no treatment.