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Postoperative Orthostatic Intolerance and Hypotension in Unilateral TKA

Postoperative Complications Clinical Trial

Official title:
Incidence of Postoperative Orthostatic Intolerance and Postoperative Orthostatic Hypotension in Patients Undergoing Unilateral Total Knee Arthroplasty

Clinical Trial Summary

Incidence of Postoperative Orthostatic Intolerance and Postoperative Orthostatic Hypotension in Patients Undergoing Unilateral Total Knee Arthroplasty

Clinical Trial Description

Early postoperative mobilization is a cornerstone in the so-called fast track multimodal perioperative approach and is essential in preventing postoperative morbidity and reducing hospital length-of-stay. Intact orthostatic blood pressure regulation is essential for early postoperative mobilization. However, early postoperative mobilization can be delayed due to postoperative orthostatic hypotension (POH) defined as a fall in systolic pressure > 20 mmHg and/or diastolic pressure > 10 mmHg or due to postoperative orthostatic intolerance (POI), characterized by dizziness, nausea, vomiting, blurred vision or syncope during mobilization. Previous prospective studies of major surgery have reported that OI and OH are common problem during early postoperative mobilization, with a prevalence of 42-50%. Retrospective studies with a less-defined mobilization protocols have reported am OI prevalence in the range of 12-60 % across surgical procedures. The aim of our study is to determine the incidence of OI during early postoperative mobilization in fast track unilateral total knee arthroplasty. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03743116
Study type Observational
Source Hvidovre University Hospital
Contact
Status Completed
Phase
Start date November 13, 2018
Completion date March 1, 2020
View Details
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