Orthopedic Disorder Clinical Trial
Official title:
Impact of Tranexamic Acid Use on Blood Loss and Transfusion Rates After Hip Reconstruction in Children, A Randomized Controlled Trial
Surgical hip reconstruction reduces the hip joint through soft tissue releases and osteotomies of the femur and/or pelvis. Blood loss and subsequent blood transfusion are normal consequences of hip reconstruction.
the use of antifibrinolytics (AFs) to limit blood loss peri-operatively has been popularized in certain subspecialties. AFs have been studied extensively in adults undergoing various orthopedic procedures including spine and total joint arthroplasty, and have been proven to reduce blood loss and reduce the risk of blood transfusion. Similarly, AFs are used in pediatric patients undergoing cardiac surgery as well as craniofacial operations. Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent that works by reversibly blocking plasminogen and thereby promoting hemostasis through the prevention of fibrin degradation. Current literature investigating the safety and effectiveness of TXA in children undergoing orthopedic procedures is limited. We hypothesize that patients treated with TXA will have reduced blood loss and transfusion requirements compared with those who did not receive TXA. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05864833 -
METabolism After Orthopedic Surgery
|
||
| Completed |
NCT03286543 -
Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System
|
N/A | |
| Recruiting |
NCT05461326 -
Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT
|
N/A | |
| Completed |
NCT06080685 -
Efficacy of Character Strengths Intervention in Enhancing Character Strengths and Self-esteem Among Adolescents
|
N/A | |
| Not yet recruiting |
NCT06326827 -
In'Oss™ (MBCP® Putty) Ortho
|
||
| Not yet recruiting |
NCT06002009 -
SupraScapular Cuff Study: Assessing the Effects of Size and Type of Rotator Cuff Tear on Suprascapular Nerve Function
|
||
| Completed |
NCT04730115 -
Evaluation of Architectural Changes in Mandibular Bone Pattern After Functional Treatment by Fractal Dimension Analysis
|
||
| Withdrawn |
NCT03436667 -
Perioperative Factors Impacting Surgical Risk and Outcomes in Children
|
||
| Completed |
NCT03299920 -
Opioid Consumption After Knee Arthroscopy
|
N/A | |
| Active, not recruiting |
NCT05075525 -
EFFECT OF HIGH INTENSITY LASER IN PATELLOFEMORAL PAIN SYNDROME
|
N/A | |
| Completed |
NCT06158165 -
Evaluating The Cardiovascular Effects of Tourniquet Application
|
||
| Recruiting |
NCT04891549 -
Tension Band Versus Locking Plate Fixation for the Treatment of Patella Fractures
|
N/A | |
| Recruiting |
NCT04676841 -
Wound Contamination During Orthopaedic Surgery
|
||
| Not yet recruiting |
NCT03899298 -
Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions
|
Phase 1 | |
| Completed |
NCT04514601 -
A Quality Improvement Project to Assess and Refine the Handover Process at Morning Trauma Meetings
|
||
| Not yet recruiting |
NCT04546594 -
Epidemiological Data on Pain
|
||
| Completed |
NCT05396924 -
Rectal Temperature Measurement in Detecting Hypothermia During Hip Arthroscopy
|
N/A | |
| Active, not recruiting |
NCT06438835 -
Development & Evaluation of Pneumatic Artificial Muscle(PAM) for Patients With Ankle Foot Orthosis(AFO)
|
N/A | |
| Active, not recruiting |
NCT05795127 -
Risk for Reoperation After First MTP Joint Arthrodesis
|
||
| Completed |
NCT04481711 -
Total Knee Arthroplasty and Clinical Findings
|
N/A |