Orthodontic Treatment Clinical Trial
Official title:
Do Adhesive Flash-free Brackets Affect Bacterial Plaque? A Randomized Controlled Clinical and Microbiological Assessment
This study aimed to compare flash-free bracket system with conventional adhesive-coated bracket system in patients with maxillary crowding.
Aim: The aim of this split-mouth study was to compare conventional and adhesive
flash-free-bracket systems in terms of plaque retention, white spot lesion formation,
biomarker levels and select microbes in gingival crevicular fluid (GCF).
Materials & Methods: Thirty-seven systemically healthy patients (18 males, 19 females) with
the age range of 13-18 years were involved in this split-mouth study. Clinical evaluations,
quantitative light-induced fluorescence (QLF) imaging, GCF and plaque samplings were
performed at baseline and at 1-, 2-, 3-months. QLF was repeated following debonding, GCF
samples were analyzed by immunoassay and real-time PCR for the biomarker and bacteria
content. Data were analyzed by Wilcoxon on dependent samples.
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