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Radiotherapy Dose De-escalation in HPV-Associated Cancers of the Oropharynx

Oropharynx Cancer Clinical Trial

Official title:
Radiotherapy Dose De-escalation in HPV-Associated Cancers of the Oropharynx Using Metabolic Signature From Interim 18FDG-PET/CT

Clinical Trial Summary

The purpose of this study is to use intra-treatment 18FDG-PET/CT during definitive radiation therapy for human papillomavirus (HPV)-related oropharyngeal cancer (OPC) as an imaging biomarker to identify and select patients with a favorable response for chemoradiation dose de-escalation. This study will prospectively evaluate the clinical outcomes for patients undergoing dose de-escalation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04667585
Study type Interventional
Source Duke University
Contact Heather Franklin, BSN, RN, OCN
Phone (919) 668-3726
Email heather.mccullough@duke.edu
Status Recruiting
Phase N/A
Start date April 12, 2021
Completion date April 2027
View Details
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