Oropharynx Cancer Clinical Trial
Official title:
A Multi-Center Phase II Trial of Individualized Adaptive De-escalated Radiotherapy Using Pre and Mid-Treatment FDG-PET/CT for HPV-related Oropharynx Cancer
This prospective study aims to utilize pre- and mid-treatment PET-CT to guide de-escalation of radiation therapy in HPV-related squamous cell carcinoma of the oropharynx.
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Status | Clinical Trial | Phase | |
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Recruiting |
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Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer
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Phase 2 | |
Completed |
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IMRT Plus Cisplatin Versus Conventional Radiotherapy Plus Cisplatin in Stage III-IV HNSCC
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Phase 3 | |
Completed |
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Recruiting |
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Immunological Function After Radiation With Either Proton or Photon Therapy
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Withdrawn |
NCT04001413 -
Therapy for High-Risk HPV 16-Positive Oropharynx Cancer Patients
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Phase 2 | |
Completed |
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Outcomes of Prophylactic Swallowing Therapy in Patients Undergoing Definitive Chemoradiation for Head and Neck Cancer
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N/A | |
Completed |
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Study of Lymphatic Drainage Mapping in Oropharyngeal Cancers
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N/A | |
Recruiting |
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QUantitative Assessment of Swallowing After Radiation (QUASAR)
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Recruiting |
NCT05793151 -
Multi-Site Trial of Navigation vs Treatment as Usual for Delays in Starting Adjuvant Therapy
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N/A | |
Active, not recruiting |
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Evaluation of De-escalated Adjuvant Radiation Therapy for Human Papillomavirus (HPV)-Associated Oropharynx Cancer
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Phase 3 | |
Active, not recruiting |
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Postoperative Radiotherapy According to Molecular Analysis of Surgical Margins of Oral and Oropharyngeal SCC
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N/A | |
Completed |
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Outpatient Ultrasound for the Diagnostic Work-up of Oropharynx Cancer
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N/A | |
Recruiting |
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Evaluation of the Benefit of a New Surgical Procedure According to IDEAL Recommendations for ORL Cancer Patients: the External Pudendal Flap Used as a New Free Flap for Oral Cavity/Oropharyngeal Reconstruction to Limit Donor Site Sequelae
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N/A | |
Active, not recruiting |
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Pembrolizumab in Combination With CRT for LA-SCCHN
|
Phase 1 | |
Completed |
NCT01108042 -
TPF-Induction Chemotherapy of Oropharyngeal and Cavity of the Mouth Cancer
|
Phase 1/Phase 2 | |
Completed |
NCT03342378 -
PET-MRI Assessment of Early Tumor Response to Predict Outcomes of HPV-Positive Oropharynx Cancer Patients
|
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Terminated |
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Prevention of Radiation-induced Severe Oral Mucositis in Oral Cavity, Oropharynx, Hypopharynx, and Cavum Cancer
|
Phase 3 | |
Completed |
NCT03418792 -
Functional Sparing of Salivary Glands Using MRI Sialography for Patients Undergoing Definitive Radiation Therapy for Head and Neck Cancers of the Oropharynx
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N/A | |
Recruiting |
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Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)
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Phase 2 | |
Recruiting |
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E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
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Phase 2 |