Effect of Pharyngeal Inhibition by rTMS on Swallowing Function

Oropharyngeal Dysphagia Clinical Trial

— rTMSvideoSS  

Official title:

Effect of Pharyngeal Cortical Area Inhibition Induced by rTMS on Swallowing Function in Healthy Subject: Video Fluoroscopic Study.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02170454
• Other study ID #: 2007/055/HP
• Status: Completed
• Phase: N/A
• First received: February 17, 2009
• Last updated: June 17, 2014
• Start date: June 2008
• Est. completion date: June 2009

Study information

• Verified date: June 2014
• Source: University Hospital, Rouen
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Direction Générale de la Santé
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to test the hypothesis that rTMS on the dominant swallowing hemisphere is able to modify swallowing coordination.

Description:

The aim of the study is to demonstrate that rTMS (on the dominant hemisphere, on the nondominant hemisphere and placebo rTMS) are able to modify swallowing coordination on healthy subjects. Swallowing function will be studied before and after rTMS with videomanometry.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: June 2009
• Est. primary completion date: November 2008
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• 18-50 years old

• healthy subjects

Exclusion Criteria:

• epilepsia

• brain injury

• stroke

• pregnancy

Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Deglutition Disorders
• Oropharyngeal Dysphagia

Intervention

Procedure:
• magnetic stimulation
rTMS on pharyngeal cortical area in healthy subjects or sham rTMS on pharyngeal cortical area in healthy subjects

Locations

Country	Name	City	State
France	VERIN	Rouen

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Rouen

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	pharyngeal pressure	Swallowing function will be studied before and after rTMS with videomanometry	Day 1	No
Secondary	swallowing time	Swallowing function will be studied before and after rTMS with videomanometry	Day 1	No