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Organic Cation Transporter 2 clinical trials

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NCT ID: NCT01237522 Completed - Metformin Clinical Trials

A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers

Start date: August 2010
Phase: Phase 4
Study type: Interventional

The aim of the study is to evaluate the pharmacokinetics of metformin in healthy Caucasians volunteers with and without the polymorphism A270S in OCT2,thus the study hypothesis is that renal clearance of metformin is affected in Caucasian with the known single nucleotide polymorphisms A270S in OCT2.