Clinical Trials Logo
  1. Home
  2. Organ Dysfunction Syndrome
  3. NCT03173196

Prospective Analysis of Septic Associated Encephalopathy Using the Non-invasive Acoustocerebrography-ACG — SAEACG  

Encephalopathy Clinical Trial

Official title:
Prospective Analysis of the Occurrence and Severity of Septic Encephalopathy in Patients With Severe Sepsis or Septic Shock, Including Non-invasive Multispectral Sonography

Clinical Trial Summary

The patients of the group "sepsis" are measured several times with the non-invasive multi-spectral sonography (Sonovum "ACG-Diagnosesystem") (days 1, 3, 7 and 14). The patients of the group "control" are measured on days 1 and 3 with the system. A measurement takes 3 minutes. For this purpose two ultrasound heads are placed above the patient's ears and fixed with an all-head harness. The device is certified for CE application. There are no known health risks of ultrasound in humans.

Clinical Trial Description

Sepsis with multiorgan failure is one of the most common diseases in intensive care units and is at the top of the world of causes of death. In addition to increasingly serious sepsis by multidrug-resistant pathogens, neurological symptoms are frequently recorded in the systemic manifestation of the disease pattern. Septic encephalopathy (SE) is usually an early cerebral sign of the developing sepsis, often before other clinically as well as diagnostically detectable findings such as fever ascent, hypotonia or laboratory chemical infections. Therefore, the SE is a clinically important parameter, also because after the sepsis, cerebral functional restrictions such as cognitive disorders can persist in the long term.

Therefore, on day 1, 3, 7 and 14 the patients are measured with the ACG-system as well as determined different scores of the patients: CAM-ICU (Confusion Assessment Method - Intensive Care Unit) and ICDSC (Intensive Care Delirium Screening Checklist) for the neurological outcome; Apache (Acute Physiology And Chronic Health Evaluation) II for mortality and SOFA (Sepsis-related Organ Failure Assessment Score) for organ failure. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03173196
Study type Observational
Source University of Rostock
Contact
Status Completed
Phase N/A
Start date June 1, 2016
Completion date July 30, 2017
View Details
See also
  Status Clinical Trial Phase
Completed NCT05114070 - Build a Decision Aid Tool to Help Emergency Intensive Care Specialists in the Context of Hypoxic Ischemic Encephalopathy
Completed NCT01425385 - Autoregulation Assessment During Liver Transplantation N/A
Terminated NCT02232958 - Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease N/A
Completed NCT04067622 - Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment N/A
Recruiting NCT04643548 - WHO Covid 19 - Neurological Abnormalities in SARS-CoV-2 ICU Patients
Recruiting NCT05519904 - Prevalence of Encephalopathy in Patients With Inflammatory Bowel Diseases
Recruiting NCT01481662 - Epidemiological, Clinical and Etiological Features of SUSAC's Syndrome N/A
Completed NCT00570973 - Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy Phase 4
Completed NCT03138876 - EEG Cap for Identification of Non-Convulsive Status Epilepticus N/A
Completed NCT04405544 - Determination of Acute Encephalopathy Predictors in Patients With COVID-19 N/A
Recruiting NCT05842616 - Cerebral Pulsatility Index Compared To Mean Arterial Blood Pressure Guided Protocol In Sepsis Induced Encephalopathy: N/A
Active, not recruiting NCT04320472 - Acute Encephalopathy in Critically Ill Patients With COVID-19
Recruiting NCT02951559 - SOLFAMU Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies Phase 4
Completed NCT02445417 - Brain Activity During Birth for Prediction of Newborns at Risk for Brain Injury
Recruiting NCT05056961 - Effects of Large Tidal Volumes Despite Minimal Inspiratory Support in Spontaneously Ventilated Intubated Resuscitation Patients. Pathophysiological Exploratory Study. N/A
Not yet recruiting NCT06368648 - CoMind Early Feasibility Study
Completed NCT00764049 - Single Pass Albumin Dialysis in Patients With Cirrhosis Phase 1/Phase 2
Completed NCT00515359 - RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies N/A
Completed NCT05259891 - eegCap Application in Paediatrics wiTh redUced GCS in REsus
Recruiting NCT04767945 - Cirrhosis Registry of Hospitalized Patients