Inpatient Colonoscopy Clinical Trial
Official title:
Pilot Study to Assess Tolerability and Feasibility of Oral Sulfate Solution (SUPREP) in Hospitalized Patients
This study will test the efficacy, tolerability, and feasibility of an oral sulfate solution
(SUPREP) for inpatient colonoscopy preparation, compared to the standard of care (GoLytely).
The hypothesis is that SUPREP will be well tolerated and non-inferior to standard
polyethylene glycol bowel preparation for colonoscopies in an inpatient setting. To test
this, at least 124 subjects who are undergoing an inpatient colonoscopy will be randomized to
receive either SUPREP or standard of care. The Boston Bowel Preparation Score will be
collected as standard of care for both groups. Safety will be monitored from standard of care
blood tests and ECG (when indicated). Subjects will be given a survey to assess how tolerable
they found the procedure.
A non-inferiority design will be used to compare SUPREP to the standard of care polyethylene
glycol preparation. Data analysis will be performed on Boston Bowel Preparation Score and
rate of failure of preparation (measured as number of successful subsequent colonoscopies).
n/a