Oral Submucous Fibrosis Clinical Trial
Official title:
Evaluation of Auto Antibodies in Oral Sub Mucous Fibrosis - a Clinico-pathological Study
Verified date | December 2017 |
Source | Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The etiology of OSMF is considered to be multifactorial. However, Role of autoimmunity had
been suggested as one of the factors but remains unproven.
The present study is undertaken to evaluate the presence of auto antibodies in OSMF patients
to pave a way for new arena of treatment with the etiology of this persistent condition
Status | Completed |
Enrollment | 70 |
Est. completion date | December 2017 |
Est. primary completion date | November 2017 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility |
Inclusion Criteria: - Patients who are willing for the study. - A positive history of chewing arecanut, and/or smoking tobacco and alcohol. - Patients with clinical and histopathological features of oral submucous fibrosis. - Patients with OSMF not under any treatment for the same Exclusion Criteria: - Unwilling patients who do not want to be part of the study. - Patients with known autoimmune disorders. |
Country | Name | City | State |
---|---|---|---|
India | Panineeya Institute of Dental Sciences | Hyderabad | Telangana |
Lead Sponsor | Collaborator |
---|---|
Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre |
India,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Evaluation of auto antibodies in oral sub mucous fibrosis | The subjects in the study suffering from oral submucous fibrosis will be clinically evaluated and graded based on criteria given by Khanna et al classification. All the subjects included in the study will also be subjected to serum analysis for presence of auto antibodies in their serum by Titerplane technique. | one and half year |
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