Hydrogen Sulfide Production by Oral Microflora

Oral Malodor (Halitosis) Clinical Trial

Official title:

Detection of Hydrogen Sulfide Production by Oral Microflora Samples

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00396539
• Other study ID #: 29.12.06-19-HMO-CTIL
• Status: Completed
• Phase: N/A
• First received: November 6, 2006
• Last updated: February 1, 2009
• Start date: January 2007
• Est. completion date: September 2008

Study information

• Verified date: November 2006
• Source: Hadassah Medical Organization
• Contact: n/a
• Is FDA regulated: No
• Health authority: Israel: Israeli Health Ministry Pharmaceutical Administration
• Study type: Observational

Clinical Trial Summary

Oral malodor is a common condition. In most cases this condition results from the proteolytic activity of anaerobic oral bacteria. These bacteria produce volatile sulfide compounds which are fowl smelling and are felt during exhalation and speech. the aim of the present study is to examine a simple method of detecting these bacteria in samples taken from the oral cavity of oral malodor patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: September 2008
• Est. primary completion date: August 2008
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• oral malodor patients

Exclusion Criteria:

• smokers, users of antibiotic one month prior to study

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

• Oral Malodor (Halitosis)

Locations

Country	Name	City	State
Israel	Hadassah Medical Organization	Jerusalem

Sponsors (1)

Lead Sponsor	Collaborator
Hadassah Medical Organization

Country where clinical trial is conducted

Israel,