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NCT05403216 Clinical Trial

Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases

Oral Lichen Planus Clinical Trial

Official title:
Clinical Value of the Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05403216
Other study ID # I20210609
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date December 1, 2022
Est. completion date December 31, 2024

Study information
Verified date August 2023
Source The Dental Hospital of Zhejiang University School of Medicine
Contact Fangman Chen
Phone 87219025
Email chenfangman@zju.edu.cn
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

On the basis of previous studies, a validation cohort will be established to explore the relationship between oral lichen planus and autoimmune thyroid diseases, and a disease efficacy prediction strategy can be formed.

Description:

For oral lichen planus patients, the prevalence of Hashimoto's thyroiditis will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined. Besides, for patients with Hashimoto's thyroiditis, the prevalence of oral lichen planus will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date December 31, 2024
Est. primary completion date December 31, 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: - OLP patients without systemic disease Exclusion Criteria: - OLP patients with severe periodontal disease

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• no intervention

Locations
Country Name City State
China The Stomatology Hospital, Zhejiang University School of Medicine Hangzhou Zhejiang

Sponsors (1)
Lead Sponsor Collaborator
The Dental Hospital of Zhejiang University School of Medicine

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary Oral lichen planus (OLP) lesions record Record changes of lesions based on the symptoms and signs of the oral lichen planus patient. 1 year
Primary Level of thyroid function and antibody The levels of thyroid hormone and thyroid autoantibodies in serum of OLP patients were detected. 1 year
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