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NCT04785703 Clinical Trial

Prolactin Hormone in Oral Lichen Planus

Oral Lichen Planus Clinical Trial

Official title:
Prolactin Hormone in Oral Lichen Planus Tissue Samples

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04785703
Other study ID # REC18-048
Secondary ID
Status Completed
Phase
First received
Last updated
Start date June 19, 2020
Est. completion date December 10, 2020

Study information
Verified date March 2021
Source October University for Modern Sciences and Arts
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Oral lichen planus (OLP) is one of the most common mucosal diseases with autoimmune etio-pathogenesis with involvement of various cytokines similar to psoriasis.It generally occurs more commonly in females, in a ratio of 3:2. prolactin (PRL),It is a peptide hormone that has a role in autoimmune related diseases like systemic lupus erythematosus and , rheumatoid Artheritis. The role of PrL in OLP pathogenesis was never investigated.the aim of this study is to investigate the expression of PRL receptors in tissue biopsies of OLP patients.

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date December 10, 2020
Est. primary completion date August 22, 2020
Accepts healthy volunteers No
Gender All
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria: - patients with oral lichen planus - systemically healthy Exclusion Criteria: - oral lichenoid lesions

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Egypt October University for modern sciences and arts Giza

Sponsors (2)
Lead Sponsor Collaborator
October University for Modern Sciences and Arts Al-Azhar University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary prolactin receptors expression in oral mucous membrane immuno-histochemistry 24 hours
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