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The Effect of Topical Curcumin Versus Topical Corticosteroid on Management of Oral Lichen Planus Patients

Oral Lichen Planus Clinical Trial

Official title:
The Effect of Topical Curcumin Versus Topical Corticosteroid on Pain, Clinical Parameters and Salivary Level of IL-33 in Oral Lichen Planus Patients: A Randomized Controlled Clinical Trial

Clinical Trial Summary

Introduce a new anti-inflammatory and antioxidant paste preparation (curcumin paste) in the management of Oral lichen planus.

- Assess the efficacy of this preparation on pain, clinical parameter and the level of IL-33 in saliva.

- Compare the outcome of new preparation with the gold standard treatment (corticosteroids).

Clinical Trial Description

Two groups will be prepared then decision of which one take curcumin paste will be selected according to randomized numbers in a sequentially numbered, opaque, sealed envelope

1 group will take topical corticosteroid and 1 will take curcumin paste then IL-33 level in saliva will be measured at the base line and at the end of 4th week pain and clinical parameters will be measured at 2nd and 4th week ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03877679
Study type Interventional
Source Cairo University
Contact
Status Not yet recruiting
Phase Phase 1
Start date May 1, 2019
Completion date June 1, 2020
View Details
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