Oral Lichen Planus Clinical Trial
Official title:
The Effect of Topical Curcumin Versus Topical Corticosteroid on Pain, Clinical Parameters and Salivary Level of IL-33 in Oral Lichen Planus Patients: A Randomized Controlled Clinical Trial
Introduce a new anti-inflammatory and antioxidant paste preparation (curcumin paste) in the
management of Oral lichen planus.
- Assess the efficacy of this preparation on pain, clinical parameter and the level of
IL-33 in saliva.
- Compare the outcome of new preparation with the gold standard treatment
(corticosteroids).
Two groups will be prepared then decision of which one take curcumin paste will be selected
according to randomized numbers in a sequentially numbered, opaque, sealed envelope
1 group will take topical corticosteroid and 1 will take curcumin paste then IL-33 level in
saliva will be measured at the base line and at the end of 4th week pain and clinical
parameters will be measured at 2nd and 4th week
;
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