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Clinical Trial Summary

The aim of the study is to assess the effect of oral foams on salivary pH changes after Coca-cola consumption in young adults.


Clinical Trial Description

This will be a cross-over clinical trial assessing the effect of oral foams containing zink hydroxiapatite and probiotics (Lactobacillus, Bifidobacterium), Olaflur (amino fluoride), and oral spray with alkaline thermal water. The study will be conducted in six visits over a period of 1.5 months. After enrolment, dental examination will be performed using the following indices: DMFT, OHI-S index, Bleeding index. Saliva buffer capacity, salivary flow rate, and baseline salivary pH will be measured. Salivary pH changes will be registered after consumption of Coca-cola alone or followed by each of the tested products application. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06148662
Study type Interventional
Source I.M. Sechenov First Moscow State Medical University
Contact
Status Completed
Phase Phase 4
Start date December 1, 2023
Completion date January 25, 2024

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