Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to determine if an oral probiotic tablet taken once a day for twelve weeks can decrease the numbers of bacteria that are associated with tooth decay and gum disease in a dentally healthy, young adult population.


Clinical Trial Description

There are over 500 types of bacteria in the mouth. Most of these bacteria do not cause disease. However, some mouth bacteria can cause tooth decay and gum disease. The purpose of a probiotic tablet for the mouth is to put known healthy bacteria in the mouth. This study will compare the effect of the probiotic tablet on the levels of harmful or disease causing bacteria in the mouth to a placebo tablet that does not contain any probiotic bacteria. ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor)


Related Conditions & MeSH terms


NCT number NCT01520974
Study type Interventional
Source Oragenics, Inc.
Contact Marilynn Rothen, RDH, MS
Phone 206-685-8132
Email rothen@uw.edu
Status Recruiting
Phase N/A
Start date January 2012

See also
  Status Clinical Trial Phase
Recruiting NCT06099574 - A Study on the Oral Health Status of Pregnant Women With Gestational Diabetes and Its Correlation With Oral Flora
Completed NCT00651248 - Evaluation of Salivary Flow and Buffer Capacity Associated to Aged People's Oral Health N/A
Completed NCT00299598 - Clinical Study of Antibacterial Nanoparticles Incorporated in Composite Restorations Phase 2
Completed NCT05046210 - The Effectiveness of Lay Health Advisors Strategy Intervention on Aborigines Elderly Oral Care Education N/A
Active, not recruiting NCT06457724 - Lactobacillus Brevis Oral Health N/A
Active, not recruiting NCT05124587 - Prediction for Critical Outcomes of Patients With COVID-19
Completed NCT03480516 - Comparison of Caries Arrested & Prevented Among SDF, NaF Varnish and Combination in Children N/A
Recruiting NCT04140929 - Oral Health Improvement for Nursing Home Residents Through Delegated Remotivation and Reinstruction N/A
Completed NCT05330793 - The Effects of an Oral Probiotic Intervention With or Without a Novel ADP-1 Toothpaste N/A
Completed NCT04289337 - Double-blind Clinical Trials of Probiotic Products in Oral Health. N/A
Not yet recruiting NCT06073392 - Cluster RCT on the Effect of the Topics Number in Oral Health Educational Video Among Preschool Children. N/A
Completed NCT00103493 - Oral Health Education Program Phase 3
Enrolling by invitation NCT06080672 - The Effect of Disclosing Dental Plaque on Plaque Index and Gingival Index in Faculty of Dentistry Students N/A
Completed NCT05755152 - Fruit-based Chewing Gums for Improving Oral Health N/A
Completed NCT05515510 - Acceptance and Efficacy of a Digital Application Among Parents to Control Early Childhood Caries N/A
Completed NCT03587428 - Effect of Two Toothpastes on Bacteria in Saliva N/A
Active, not recruiting NCT01514552 - The Use of Functional Confections in Promoting Oral Health Phase 1
Enrolling by invitation NCT06124222 - Prosthetic Rehabilitation and Its Influence on Masticatory Performance and QoL in Patients Treated for HNC N/A
Completed NCT05695443 - Oral Health in Prison: a Study on Improving Prisoners' Oral Health N/A
Completed NCT03141554 - The Effect of Oral Antiseptic Gargles on the Oral Cavity Microbiome Phase 4