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Oral Bacterial Infection clinical trials

View clinical trials related to Oral Bacterial Infection.

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NCT ID: NCT06193512 Recruiting - Clinical trials for Mechanical Ventilation Complication

Efficacy of A Novel RinSe Device to Reduce Oral Bacteria in Intubated IntEnsive CaRe Patients: a Pilot Study

EASIER
Start date: March 8, 2024
Phase: N/A
Study type: Interventional

We propose a randomized pilot/feasibility study comparing oral care treatment as usual (TAU) with Swiftsure SwishKit plus oral care TAU on the presence and magnitude of bacterial load in the oropharyngeal space in orotracheally intubated patients. The trial will be conducted with IRB approval and written consent from patient or its legal representative.

NCT ID: NCT05628571 Not yet recruiting - Clinical trials for Oral Bacterial Infection

Evaluation of the Antibacterial Effect of a Toothpaste Containing Zinc Lactate

Start date: February 1, 2023
Phase: Phase 3
Study type: Interventional

The aim of this study is to evaluate the antibacterial effect 12 hours after 4-week use of a toothpaste containing amine base, zinc lactate, and fluoride. For this, healthy people will be invited to use two different toothpaste: control - containing only fluoride; test - containing fluoride plus a combination with zinc. The primary outcome is the efficacy of the test toothpaste in the oral bacterial load reduction in samples of saliva and oral mucosa (obtained through scraping); the second outcome is effect of the test toothpaste in the expression of mucin in the oral mucosa.

NCT ID: NCT05603650 Recruiting - Clinical trials for Microbial Colonization

Effects of Mouthrinses on the Microbiome of the Oral Cavity and GI Tract

Microbiome
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this research study is to identify the effects of 2 over-the-counter mouthwashes on bacteria and 3 viruses in the participant's mouth and gut. The participant will be randomly allocated to rinse their mouth twice daily either with Listerine mouthwash, Lumineux Oral Essentials mouthwash, or water. The overall duration of the study will be approximately 180 days and will include approximately 5 visits and 15-30 minutes for each visit with a total of approximately 2.5 hours of your time. Additionally, fecal matter will also be collected in some subjects using a commercial collection kit.

NCT ID: NCT05401201 Recruiting - Dental Plaque Clinical Trials

Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLP

RELIEF-OLP
Start date: February 24, 2023
Phase: N/A
Study type: Interventional

This study is designed to investigate the effectiveness of plaque control intervention by home-use dual-light aPDT Lumoral -device as an adjunctive or alternative treatment to triamcinolone acetonide (TCA) mouth rinse or other topical corticosteroid treatment on the symptoms and clinical appearance of symptomatic gingival involvement of oral lichen planus (OLP).

NCT ID: NCT04077606 Not yet recruiting - Clinical trials for Gingival Inflammation

Gingival Inflammatory Response,Bacterial Adhesion and Patient Satisfaction of Ceramo-metallic vs Zirconia Crowns

CairoU
Start date: November 1, 2019
Phase: N/A
Study type: Interventional

Ceramo metallic restoration has proved high success rate over past years as considered to be the gold standard while Monolithic zirconia as fixed dental prostheses have gained attention because of their good fracture strength, low wear of the enamel antagonist and pleasant color .Material composition will affect gingival health and biofilm formation which initiate caries and periodontal diseases.

NCT ID: NCT03998865 Completed - Clinical trials for Peri-implant Mucositis

Bacterial Microbiota Characterization on Implant-supported PEEK and Titanium Provisional Abutments

Start date: May 8, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to determine the relative abundances of the different bacterial phyla and families in the microbiota present on the surface of PEEK implant-supported provisional abutments compared to titanium implant-supported provisional abutments, as well as the effect of both materials on the presence of antibiotics resistance genes.

NCT ID: NCT02988349 Completed - Dental Caries Clinical Trials

Ecological Effect of Arginine Dentifrice on Oral Microbiota

Start date: October 2013
Phase: N/A
Study type: Interventional

caries-free (CF) individuals caries-active (CA) individuals (DMFT ≥ 6) will be recruited. Subjects will be instructed to brush their teeth twice daily for 3 min using Colgate® Sensitive Pro-Relief® toothpaste (containing 8% arginine and 1450 ppm NaF) for 2 weeks. Supra- and subgingival plaque, saliva, and in situ plaque samples will be collected before and after the treatment for laboratory analyses.