Multiphoton Laser Scanning Microscopy in Cutaneous Optical Pathology

Optical Biopsy Clinical Trial

Official title:

Multiphoton Laser Scanning Microscopy in Cutaneous Optical Pathology

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT00508781
• Other study ID #: 9100206857
• Status: Recruiting
• Phase: N/A
• First received: July 26, 2007
• Last updated: July 26, 2007
• Start date: November 2002
• Est. completion date: December 2012

Study information

• Verified date: November 2002
• Source: National Taiwan University Hospital
• Contact: Shiou-Hwa Jee, MD PhD
• Phone: +886-2-23123456
• Email: shiouhwa[@]ha.mc.ntu.edu.tw
• Is FDA regulated: No
• Health authority: Taiwan: Department of Health
• Study type: Observational

Clinical Trial Summary

We use multiphoton laser scanning microscopy to observe cutaneous anatomy and pathology. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy.

Description:

For skin diseases, the most convincing method for diagnosis to date is surgical biopsy. However, a skin biopsy is an invasive procedure which carries the risk of tissue damage, wound infection and scar formation. To solve the inconvenience from surgical biopsy, multiphoton laser scanning microscopy is a developing, non-invasive method for observing the cutaneous anatomy and pathology. Multiphoton laser scanning microscopy is good in tissue penetration and resolution with less tissue damage. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy. A good correlation in multiphoton image may serve as optical biopsy for cutaneous pathology and spare the invasive procedure of skin biopsy.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 400
• Est. completion date: December 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 1 Year to 90 Years

Eligibility

Inclusion Criteria:

• Patients receiving cosmetic surgeries such as removal of moles

Exclusion Criteria:

• No special exclusion criteria

Study Design

Primary Purpose: Screening, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Cutaneous Pathology
• Dermatopathology
• Optical Biopsy

Intervention

Behavioral:
• Multiphoton laser image in cutaneous pathology

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei

Sponsors (3)

Lead Sponsor	Collaborator
National Taiwan University Hospital	National Health Research Institutes, Taiwan, National Science Council, Taiwan

Country where clinical trial is conducted

Taiwan,