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Clinical Trial Summary

The purpose of this study is to find out whether avutometinib is a safe treatment for advanced or recurrent solid tumor cancers in children and young adults. Researchers will look for the highest dose of avutometinib that is safe and cause few or mild side effects.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Brain Neoplasms
  • Central Nervous System Neoplasms
  • Central Nervous System Tumor
  • CNS Tumor, Adult
  • CNS Tumor, Childhood
  • CNS Tumors
  • Glioma
  • Low-grade Glioma
  • Neoplasms
  • Nervous System Neoplasms
  • Neuroblastoma
  • Neurofibroma
  • Neurofibroma, Plexiform
  • Neurofibromatoses
  • NF1
  • Optic Pathway Gliomas
  • Plexiform Neurofibroma
  • Primary Brain Tumor
  • Refractory Cancer
  • Solid Carcinoma
  • Solid Tumor
  • Solid Tumor, Adult

NCT number NCT06104488
Study type Interventional
Source Memorial Sloan Kettering Cancer Center
Contact Sameer Farouk Sait, MD
Phone 212-639-3449
Email faroukss@mskcc.org
Status Recruiting
Phase Phase 1
Start date October 20, 2023
Completion date October 20, 2029

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