Opioid Use Disorder Clinical Trial
Official title:
An Open-Label Multicenter Study Assessing the Long-Term Safety of a Once-Weekly and Once-Monthly, Long-Acting Subcutaneous Injection Depot of Buprenorphine (CAM2038) in Adult Outpatients With Opioid Use Disorder
Open-label multi-center, 48 week safety study, consistent with standard practice for long-term safety studies. This one year safety study will utilize CAM2038 q1w (once weekly) and q4w (once monthly) and will have 3 phases: Screening, Treatment, and Follow-up.
Open-label multi-center, 48 week safety study, consistent with standard practice for
long-term safety studies. This one year safety study will utilize CAM2038 q1w (once weekly)
and q4w (once monthly) and will have 3 phases: Screening, Treatment, and Follow-up.
Patients who are currently taking sublingual (SL) BPN (weekly or monthly prescription visits)
or individuals who are actively seeking BPN treatment but who have not yet begun a treatment
regimen, may be eligible for the study.
Following Screening, qualified subjects meeting inclusion criteria and not meeting exclusion
criteria will be initiated on either CAM2038 q1w or q4w, based on their current treatment
status (qualified subjects currently on SL BPN or seeking BPN treatment). Qualified subjects
will be initiated or transitioned to CAM2038 q1w or q4w as follows:
Initiation of BPN treatment - initiate with CAM2038 q1w
Currently receiving SL BPN treatments - transfer to corresponding CAM2038 q1w or q4w dose
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06021431 -
Virtual Reality Cognitive-Affective Training for Opioid Use Disorder- A Phase 2 RCT
|
N/A | |
| Completed |
NCT06266572 -
Overcoming Stigma and Improving Outcomes for SUDs Through Education, Engagement, and Empowerment
|
Phase 1 | |
| Recruiting |
NCT05037682 -
Pain and Opioid Management in Older Adults
|
N/A | |
| Completed |
NCT06200740 -
Remotely Observed Methadone Evaluation
|
N/A | |
| Not yet recruiting |
NCT06441604 -
Extended-release Buprenorphine as a Novel Low-dose Induction Strategy
|
Phase 2 | |
| Recruiting |
NCT06028126 -
Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial
|
N/A | |
| Completed |
NCT02559973 -
Pharmacokinetics, Safety, and Tolerability of Depot Buprenorphine at Three Different Molecular Weights in Treatment-Seeking Subjects With Opioid Use Disorder
|
Phase 1 | |
| Completed |
NCT02593474 -
Medication-Assisted Treatment for Youth With Substance Use Disorders
|
Phase 1 | |
| Completed |
NCT02440256 -
Expanded HIV Care in Opioid Substitution Treatment (EHOST) Trial
|
N/A | |
| Completed |
NCT05587998 -
A Study to Assess the Effect of AZD4041 on Respiratory Drive in Recreational Opioid Users.
|
Phase 1 | |
| Terminated |
NCT04577144 -
An Observational Study of Environmental and Socioeconomic Factors in Opioid Recovery - Long Term
|
||
| Recruiting |
NCT06001437 -
Following Outcomes Remotely Within Addiction Recovery Domains
|
||
| Recruiting |
NCT05976646 -
Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
|
Phase 1/Phase 2 | |
| Completed |
NCT05546229 -
Assessment of Methadone and Buprenorphine in Interstitial Fluid
|
||
| Not yet recruiting |
NCT06416020 -
Integrating MOUD in African American Community Settings (Better Together)
|
N/A | |
| Not yet recruiting |
NCT06104280 -
Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment
|
N/A | |
| Recruiting |
NCT06206291 -
Cannabidiol for Opioid Addiction
|
Phase 2 | |
| Completed |
NCT05552040 -
START NOW in the Treatment of Opioid Addicted Individuals
|
N/A | |
| Recruiting |
NCT05459922 -
Adjunctive Bright Light Therapy for Opioid Use Disorder
|
N/A | |
| Recruiting |
NCT05343169 -
Community-based Education, Navigation, and Support Intervention for Military Veterans
|
N/A |