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Clinical Trial Summary

This study is a prospective randomized trial examining the effect of topically combined antifibrinolytics (Tranexamic acid) with local anesthetics in all electively created surgical wound beds in hand surgery to provide long term pain relief and decrease the use of postoperative narcotics.


Clinical Trial Description

The aim of the study is to provide long term pain relief and decrease the use of postoperative narcotics. All treatments are applied topically to the surgical bed prior to closure of the skin. Each of the drugs used in this study are Food and Drug Administration (FDA) approved and routinely used for pain relief. However, the route of administration of the drugs and addition of tranexamic acid or aminocaproic acid is considered off-label (outside of the FDA-approved indications) and therefore investigational. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04814433
Study type Interventional
Source NYU Langone Health
Contact
Status Terminated
Phase Phase 4
Start date March 24, 2021
Completion date July 10, 2023

See also
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Completed NCT02737826 - Discontinuation From Chronic Opioid Therapy For Pain Using a Buprenorphine Taper N/A