The Influence of Tramadol on Opioid-induced Bowel Dysfunction

Status Completed

Clinical Trial Summary

Tramadol is a weak opioid and widely used to treat moderate to severe pain. Stronger opioids are known to inhibit gastrointestinal motility and secretion, however the effects of tramadol on gastrointestinal function remains less understood. The aim of this study was to determine to what degree tramadol causes opioid-induced bowel dysfunction by using an objective design to explore gastrointestinal transit, motility pattern, secretion, and colonic volume, in a group of healthy male volunteers.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06385561
Study type	Interventional
Source	Aalborg University Hospital
Contact
Status	Completed
Phase	Phase 2
Start date	August 11, 2022
Completion date	May 15, 2023

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