Linking Hospitalized Injection Drug Users to Buprenorphine

Status Completed

Clinical Trial Summary

This study tests whether starting Suboxone (buprenorphine) during a medical hospitalization, and then providing an appointment (a "link") for after discharge to maintenance buprenorphine in an outpatient setting will reduce HIV risk behavior in individuals who inject opioids.

Clinical Trial Description

In this randomized controlled trial, medically hospitalized opioid dependent patients will be assigned to a "treatment as usual" group, where they will receive a detox regiment of Suboxone during their hospital stay, or a "linkage" group, where they receive a maintenance course of Suboxone during their hospital stay, and appointment post-discharge with an outpatient Suboxone clinic/provider and a Suboxone prescription to use between discharge and this appointment. Study interviews are completed at baseline, and 1, 3- and 6-months post-baseline. Primary outcomes are opioid use and HIV risk behavior. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Opiate Dependence

Clinical Trial Details

NCT number	NCT00987961
Study type	Interventional
Source	Butler Hospital
Contact
Status	Completed
Phase	Phase 3
Start date	September 2009
Completion date	September 2015

View Details

See also
Status	Clinical Trial	Phase
Terminated	`NCT03538444` - Repetitive Transcranial Magnetic Stimulation for Opiate Use Disorder	N/A
Completed	`NCT01690546` - Low Dose Naltrexone-buprenorphine Transfer to Vivitrol Injection in Opioid Dependence	Phase 2
Completed	`NCT01389167` - Naltrexone and Behavioral Drug and HIV Risk Reduction Counseling in Russia	Phase 3
Completed	`NCT01442493` - Reengineering Methadone Treatment Study of Patient-centered Methadone Treatment	N/A
Completed	`NCT01182402` - Electronic Compliance Monitoring in Opioid Substitution Treatment	N/A
Completed	`NCT00634803` - Clinical Trial of Integrated Treatment for Pain and Opioid Dependence	Phase 1/Phase 2
Completed	`NCT00539123` - Drug Counseling and Abstinent-Contingent Take-Home Buprenorphine in Malaysia	N/A
Completed	`NCT00757744` - Behavioral Drug and HIV Risk Reduction Counseling in Methadone Patients in China	Phase 3
Completed	`NCT00577408` - Behavioral Naltrexone Therapy for Promoting Adherence to Oral Naltrexone vs Extended Release Injectable Depot Naltrexone	Phase 3
Completed	`NCT00566969` - Cocaine Withdrawal and Pharmacotherapy Response	N/A
Recruiting	`NCT00241930` - Integrating Buprenorphine Into HIV Treatment	Phase 4
Completed	`NCT00218621` - The Effects of Methadone and Buprenorphine on Fetal Neurobehavior and Infant Neonatal Abstinence Syndrome - 1	Phase 2
Completed	`NCT00406484` - Brief Introductory Therapy for Opioid Dependence	Phase 2
Completed	`NCT00580827` - Clinical Efficacy of Disulfiram in LAAM-Maintained Cocaine Abusers	N/A
Completed	`NCT03015597` - Pilot Study of Contingency Management for Smoking Cessation	N/A
Completed	`NCT01393392` - Developing a Smoking Cessation Intervention for Methadone Maintained Smokers	Phase 1
Completed	`NCT01416584` - A Bridge to Treatment: The Therapeutic Workplace and Methadone Treatment	N/A
Recruiting	`NCT00439049` - Substance Abuse Pre-Treatment Screening Study
Withdrawn	`NCT00398008` - HIV Risk Reduction and Drug Abuse Treatment in Iran	Phase 2
Completed	`NCT00622596` - Prospective Cohort of Opiate Dependent Patients on Buprenorphine/Naloxone for Maintenance	N/A